孵育鸡蛋膜对深Ⅱ度烧伤创面bFGF、EGF表达的影响及意义

陈大芳; 易凤琼; 吕碧琼

doi:10.13406/j.cnki.cyxb.2011.08.024

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孵育鸡蛋膜对深Ⅱ度烧伤创面bFGF、EGF表达的影响及意义

基础研究 | 更新时间：2024-01-17

- 孵育鸡蛋膜对深Ⅱ度烧伤创面bFGF、EGF表达的影响及意义
- Effect and significance of incubated egg membrane on the expressions of bFGF and EGF of deep second degree skin burn in rats
- 重庆医科大学学报 2011年36卷第8期页码：947-949
- 作者机构：
  
  重庆医科大学附属第一医院麻醉科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2011.08.024
  中图分类号： R644
- 纸质出版日期：2011，
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[1]陈大芳,易凤琼,吕碧琼.孵育鸡蛋膜对深Ⅱ度烧伤创面bFGF、EGF表达的影响及意义[J].重庆医科大学学报,2011,36(08):947-949.

CHEN Da-fang, YI Feng-qun, LV Bi-qiong. Effect and significance of incubated egg membrane on the expressions of bFGF and EGF of deep second degree skin burn in rats[J]. Journal of Chongqing Medical University, 2011,36(8):947-949.
[1]陈大芳,易凤琼,吕碧琼.孵育鸡蛋膜对深Ⅱ度烧伤创面bFGF、EGF表达的影响及意义[J].重庆医科大学学报,2011,36(08):947-949. DOI： 10.13406/j.cnki.cyxb.2011.08.024.

CHEN Da-fang, YI Feng-qun, LV Bi-qiong. Effect and significance of incubated egg membrane on the expressions of bFGF and EGF of deep second degree skin burn in rats[J]. Journal of Chongqing Medical University, 2011,36(8):947-949. DOI： 10.13406/j.cnki.cyxb.2011.08.024.

摘要

目的:研究孵育鸡蛋膜对大鼠深Ⅱ度烧伤创面碱性成纤维细胞生长因子（Basic fibroblast growth factor

bFGF）、上皮生长因子（Epidermal growth factor

EGF）表达的影响及意义。方法:以鸡蛋膜、暴露处理为孵育鸡蛋膜对照

测定伤后7、14、21 d创面愈合率、创面羟脯氨酸含量、EGF和bFGF表达量。结果:孵育鸡蛋膜在各时间点愈合率高于暴露组

伤后7 d EGF

bFGF表达高于对照组。结论:孵育鸡蛋膜对深Ⅱ度烧伤创面愈合有促进作用

其促愈机理与覆盖孵育鸡蛋膜后创面EGF

bFGF表达增高相关。

Abstract

Objective:To study the effect of incubated egg membrane on the expressions of bFGF and EGF in deep second degree skin burn in rats.Methods:With the egg membrane exposed as the control for the incubated egg membrane

the wound-healing rate was measured on the 7th

14th and 21st day after burn injury.The contents of hydroxyproline

and the expressions of bFGF and EGF were detected.Results:The wound healing rate of incubated egg membrane group was higher than that of exposed group.On the 7th day after burn injury

the expressions of bFGF and EGF in incubated egg membrane group were higher than those of the control group.Conclusion:Incubated egg membrane may promote the burn healing significantly

through enhancing the expressions of bFGF and EGF in the burn wound.

关键词

孵育鸡蛋膜烧伤EGFbFGF

Keywords

incubated egg membraneburnEGFbFGF

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