ZHANG Jun, et al. Determination of c-myc gene in children’s lymph node swollen diseases and its clinical significance[J]. Journal of Chongqing Medical University, 2004,(3):356-359.
ZHANG Jun, et al. Determination of c-myc gene in children’s lymph node swollen diseases and its clinical significance[J]. Journal of Chongqing Medical University, 2004,(3):356-359. DOI: 10.13406/j.cnki.cyxb.2004.03.033.
P <0 .0 5 )。②、反应性增生肿大和恶性肿瘤性肿大淋巴结组织的c -mye表达区域不同。 结论 :检测c -mye基因的表达
对鉴别恶性淋巴瘤与非肿瘤性淋巴结疾病
特别是用于和淋巴结反应性增生之间的鉴别具有一定的参考价值
Abstract
Objective:To study the expression and significance of c-myc in pediatric lymph node swollen diseases.Methods:Expression of c-myc gene in swollen lymph node specimens of 84 children with lymph node swollen diseases were determined with SP immunohistochemistry technique.Results:(1)The positivity rates of the c-myc gene of lymphadenitis
reactive hyperplasia (RH) and lymphoma were 15.62%
40.48%
and 80.00%
respectively
and the difference was significant( χ 2=14.59
P <0.05 ).(2)The region of the c-myc expression in RH and malignant lymphoma were different.Conclusion:The immunohistochemical detection of c-myc may be used to differentiate lymphoma from other lymph node swollen diseases