检测血清TRAb水平在甲状腺疾病诊治中的价值

段东; 倪济苍; 罗加; 邓红; 陶林

doi:10.13406/j.cnki.cyxb.2004.03.028

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检测血清TRAb水平在甲状腺疾病诊治中的价值

更新时间：2024-01-17

- 检测血清TRAb水平在甲状腺疾病诊治中的价值
- The value of determination of serum TRAb levels in diagnosis and treatment of patients with thyroid disease
- 重庆医科大学学报 2004年第3期页码：342-344
- 作者机构：
  
  1. 重庆医科大学临床学院核医学科
  2. 重庆医科大学临床学院核医学科,重庆,400016
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2004.03.028
  中图分类号： R581
- 纸质出版日期：2004，
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[1]段东,倪济苍,罗加,邓红,陶林.检测血清TRAb水平在甲状腺疾病诊治中的价值[J].重庆医科大学学报,2004(03):342-344.

DUAN Dong, et al. The value of determination of serum TRAb levels in diagnosis and treatment of patients with thyroid disease[J]. Journal of Chongqing Medical University, 2004,(3):342-344.
[1]段东,倪济苍,罗加,邓红,陶林.检测血清TRAb水平在甲状腺疾病诊治中的价值[J].重庆医科大学学报,2004(03):342-344. DOI： 10.13406/j.cnki.cyxb.2004.03.028.

DUAN Dong, et al. The value of determination of serum TRAb levels in diagnosis and treatment of patients with thyroid disease[J]. Journal of Chongqing Medical University, 2004,(3):342-344. DOI： 10.13406/j.cnki.cyxb.2004.03.028.

摘要

目的 :探讨检测血清TRAb水平在甲状腺疾病诊治中的价值。方法 :分别检测 30 8例甲状腺疾病患者及正常对照组的血清TRAb水平（采用RRA方法）、FT3

FT4水平及TGAb、TPOAb滴度（采用RIA方法）。结果 :血清TRAb水平及阳性率 :Graves’病发作组、缓解组及桥本氏病组均明显高于正常对照组 ;Graves’病发作组明显高于缓解组。Graves’病组TRAb水平与血清FT3、FT4水平及桥本氏病组TRAb水平与TGAb、TPOAb滴度间均无相关性。结论 :对血清TRAb水平的检测在自身免疫性甲状腺疾病

特别是Graves’病的诊断、治疗中具有重要价值。但其水平的高低却不能反映Graves’病的病情轻重

同时它也是不同于TGAb、TPOAb的另一类自身抗体

Abstract

Objective:To study the value of measurement of serum TRAb levels in diagnosis and treatment of patients with thyroid disease.Methods:The levels of serum TRAb(by RRA)

FT 3?FT 4 and titrations of TGAb

TPOAb(by RIA) were measured in 308 patients with thyroid disease as well as in 50 normal people.Results:The average levels and positive rates of serum TRAb were significantly higher in patients with Graves’ disease (including hypertyroid group and remission group) and Hashimoto’s disease than those in normal group

and the hypertyroid group were significant higher than the remission group in level and positive rate of TRAb.There were no correlations between serum TRAb levels and FT3

FT4 levels in patients with Graves’ disease

and titrations of TGAb

TPOAb in patients with Hashimoto’s disease.Conclusion:Serum TRAb level can not reflect the severity of Graves’ disease

and TRAb is another auto-antibody different from TGAb

TPOAb

but there is important value in determing the serum TRAb level in diagnosis and treatment of auto-immune thyoid disease

especially to Graves’ disease.

关键词

甲状腺疾病促甲状腺激素受体抗体（TRAb）诊断治疗

Keywords

thyroid diseaseTSH receptor antibody(TRAb)diagnosistherapy

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