Using enzyme-linked immunosorbent assay

we detected the levels of total IgE

Japanese cedar specificIgE

and Japanese cedar specific IgG subcalass in 120 patients with Japanese cedar allergic rhinitis.The resultsshowed that the levels of SIgG4(478.88±120.60ng/ml) of patients were significantly higher than those of thecontrols(P＜0.01)

and the same results were found for concentrations of specific IgG2 and IgG4.The differecebetween before-treatment and after-treatment levels of specifie IgE and specific IgG4 was also significant(specific IgE before treatment.30.60±0.78iu/ml

after treatment:1.58±0.44iu/ml P＜0.01

specific IgG4 before treat.mentt478.88±120.60ng/ml

after treatment.292.10±101.18ng/ml P＜0.01).We conclude that specific IgG subclasseshave obvious etiological specificity and sensitivity.