UITRASTRUCTURAL STUDIES ON HYPOPLASTIC LUNGS IN FETAL RABBIT WITH EXPERIMENTAL DIAPHRAGMATIC HERNIA[J]. Journal of Chongqing Medical University, 1993,(2):112-114.
UITRASTRUCTURAL STUDIES ON HYPOPLASTIC LUNGS IN FETAL RABBIT WITH EXPERIMENTAL DIAPHRAGMATIC HERNIA[J]. Journal of Chongqing Medical University, 1993,(2):112-114. DOI: 10.13406/j.cnki.cyxb.1993.02.005.
Left-sided diaphragmatic hernias were created in 9 rabbit fetus at 23-26 day’s gestation
and were returned to their original amnioaic sac for further development until the 29 days’ gestation for cesarrean section to obtain living fetus. During the creation of the diaphragmatic hernias
13 normal fetus at a littet with the operated fetus were taken for morphological study of the stages of lung development. Electron microscopic obser vations in 9 diaphragmatic hernias demonstrated marked delay in the development of alvesli and at term the lung had small
thick-walled terminal air spaces with few cappillaries and no true alveoli when compared With the thinwalled alveoli in normal lungs. Another striking feature was an appearent increase in the frequency of type 11 albeolar. cells in diaphragmaric hernia lungs. Furthermore
the delay in the develoment of alveoli was more marked at 23 days’ geslation to creat the hernia than at later days