Objective To explore the effect of the information technology-based chest pain center in the care of patients with ST-elevation myocardial infarction（STEMI）

so as to provide a reference for clinical treatment. Methods Ninety patients with STEMI who visited the Chest Pain Center of the Fifth People’s Hospital of Dalian from October 2018 to October 2020 were selected as the study subjects. Study subjects who attended the hospital in October 2018-October 2019 were selected in the control group（n=47） and those who attended the hospital in November 2019-October 2020 in the intervention group（n=43）. Patients in the control group received routine care and patients in the intervention group received information technology-based chest pain center intervention based on the control group. The First Medical Contact-to-ECG（FMC2ECG） time

door-to-balloon（D2B） time

and length of hospital stay were compared between the 2 groups. The success rate of rescue and readmission rate within 6 months were compared between the 2 groups. Quality of life was assessed before and after intervention（at discharge） using the Short Form-36（SF-36）. Results FMC2ECG

D2B

and hospital stay in the intervention group were significantly shorter than those in the control group（P<0.05）. The success rate of rescue in the intervention group was significantly higher than that in the control group（P<0.05）. The readmission rate of patients in the intervention group was significantly lower than that in the control group（P<0.05）. Before the intervention

there was no significant difference in mental health

physical health

physical activity

emotional role

social relationship

and vitality scores in the SF-36 between the two groups（P>0.05）. After the intervention

the scores of mental health

physical health

physical activity

emotional function

social relationship

and vitality in the SF-36 in the two groups were significantly higher than those before the intervention

with the intervention group higher than the control group（P<0.05）. Conclusion The application of an information technology-based chest pain center in patients with STEMI is effective

which can shorten FMC2ECG

D2B

and hospital stay

improve the success rate of rescue and quality of life

and reduce the readmission rate within 6 months. These benefits justify a wider application clinically.