Objective To explore the effectiveness of positive psychological interventions based on the PERMA model of wellbeing on the level of fear of cancer recurrence and subjective well-being of young and middle-aged patients with breast cancer.Methods One hundred and fourteen breast cancer patients admitted to a hospital in Nanyang from October 2019 to October 2020 were selected for the study.Patients were divided into a control group and a research group

with 57 cases in each group.Patients in the control group received conventional health education

and patients in the study group received positive psychological intervention based on the PERMA model of well-being on the basis of conventional health education

and both groups received consecutive intervention for 8 weeks.The Fear of Progression Questionnaire-Short Form（Fo P-QSF） scores

Positive Psycap Questionnaire（PPQ） scores

and subjective Index of Well-Being（IWB） scores were compared between the 2 groups before and after the intervention.Results After the intervention

the total score of PPQ and the scores of each dimension

the total score of IWB and the scores of each dimension in the study group were higher than those in the control group

and the differences were statistically significant（P <0.05）.After the intervention

the Fo P-Q-SF scores

physical health scores

and social and family dimensions scores of patients in the study group were lower than those in the control group

and the differences were statistically significant（P<0.05）.Conclusion Positive psychological interventions based on the PERMA model of well-being can significantly improve the levels of psychological capital and subjective well-being of young and middle-aged patients with breast cancer and reduce their fear of cancer recurrence.