Objective To explore the effect of steped nursing based on mindfulness motivation in nursing care of patients with cancer-related pain.Methods A total of 106 patients with cancer-related pain treated in a hospital in Zhengzhou from July 2019 to July 2020 were randomly divided into routine group and study group

with 53 cases in each group.Patients in the routine group were given routine nursing

while patients in the study group were intervened with stepped nursing based on mindfulness motivation on the basis of routine nursing.Patients in both groups were given nursing continuously for one month.The pain score before and after nursing

the pain relief after nursing and the influence of pain on all aspects of life were compared between the two groups

and the nursing satisfaction of the two groups were compared.Results Before nursing

there was no significant difference in pain score between the two groups（P>0.05）

however

after nursing

the pain score in the two groups was lower than that before nursing

and the pain score in the study group was lower than that in the routine group

and the difference was statistically significant（P<0.05）.There was significant difference in the grade distribution of pain relief rate between the two groups（P<0.05）

and the pain relief rate in the study group was significantly higher than that in the routine group

and the difference was statistically significant（P<0.05）.Before nursing

there was no significant difference in the scores of pain on all aspects of life between the two groups（P>0.05）

however

after nursing

the scores of pain on sleep

activity

emotion and appetite in the two groups were lower than those before nursing

and the scores in the study group were lower than those in the routine group

and the differences were statistically significant（P<0.05）.There was significant difference in the grade distribution of nursing satisfaction between the two groups（P<0.05）

and the nursing satisfaction of patients in the study group was significantly higher than that in the routine group

and the differences were statistically significant（P<0.05）.Conclusion In the nursing care of patients with cancer-related pain

stepped nursing based on mindfulness motivation can significantly relieve patients’ pain symptoms

reduce the impact of pain on patients’ life

and improve patients’ pain relief rate and nursing satisfaction

which is worth popularizing in clinical practice.