SUN Yujie, LI Hui, XI Ranran, et al. Medication characteristics of East Mountain Villa Basis by Xin’an medical practitioner Ye Xijun:An analysis based on data mining[J]. Journal of Southwest Medical University, 2020,43(6):623-627.
SUN Yujie, LI Hui, XI Ranran, et al. Medication characteristics of East Mountain Villa Basis by Xin’an medical practitioner Ye Xijun:An analysis based on data mining[J]. Journal of Southwest Medical University, 2020,43(6):623-627.DOI:
Objective:To analyze and explore the medication ideas of Xin’an medical practitioner Ye Xijun embodied in East Mountain Villa Basis by data mining
and to develop the modern clinical medication thinking.Methods:We collected and summarized the prescription drugs in East Mountain Villa Basis by Ye Xijun
conducted frequency statistics of drugs clinically used by Ye using Office 2010
and performed association rule analysis and cluster analysis using Apriori algorithm in IBM SPSS Modeler 14.1 and IBM SPSS 22.0
respectively
to extract Ye’s main medication ideas.Results:Among the 328 prescriptions collected
278 drugs were involved
and they were used a total of 3490 times.The drugs used were mainly of cold nature and sweet taste and mostly entered the spleen(stomach)meridian.The three most frequently used drugs were tangerine peel
Poria cocos
and snakegourd peel.The analysis of common drug combinations suggested 20 combinations including Poria cocos/tangerine peel and tangerine peel/Rhizoma Pinelliae Praeparatum.The cluster analysis suggested 12 drug combinations including Radix Paeoniae Rubra/Forsythia suspensa/Artemisia capillaris and Radix Puerariae/chrysanthemum.Binomial and trinomial association rule analyses of the 39 most frequently used drugs suggested 14 and 11 combinations
respectively.Conclusion:Ye’s clinical practice emphasizes strengthening the spleen and stomach to protect the acquired foundation
excels in clearing lung heat and moistening lung dryness to treat febrile diseases and lung diseases
emphasizes the passage of Qi to dispel the evil of phlegm and dampness
and excels in elucidating the pathogenesis of disease from the aspect of violation or reverse restriction in five elements and treating the disease accordingly.
关键词
叶熙钧东山别墅医案数据挖掘聚类分析关联规则用药特色
Keywords
Ye XijunEast Mountain Villa BasisData miningCluster analysisAssociation rulesMedication characteristics