Objective To investigate the clinical effect of lactobacillus live capsules in the treatment of bacterial vaginosis（BV）during pregnancy and its effect on the outcome of pregnancy.Methods A total of 339 pregnant patients with BV who admitted a hospital in chongqing from March 2017 to February 2018 were selected as the study subjects.Of the 339 gestational patients

80 refused the of metronidazole orally and lactobacillus live capsule treatment

which was set as control group A

and the remaining 259 gestational BV patients were divided into 2 groups according to the random number table method

control group B（n=130）and observation group（n=129）.Patients in control group A were treated with honghe lotion.Patients in control group B were treated with metronidazole orally.The observation group was treated with lactobacillus live capsule.To compare the effect of the three groups at 4 weeks after drug withdrawal

to compare the outcomes of pregnancy.Results The effective rates of treatment in the observation group and control group B were 84.5%and 62.3% when the drugs were discontinued for 4 weeks

both of which were higher than 32.5%in control group A.And the effective rates of treatment in the observation group were higher than that in control group B

with statistically significant differences（P<0.05）.The incidence of adverse pregnancy outcomes in the observation group and control group B was 13.20% and 17.69%

which were both lower than 47.50%in control group A

with statistically significant differences（P<0.05）.There was no statistically significant difference between control group B and observation group（P>0.05）.Conclusion The efficacy of lactobacillus live capsules in reducing the adverse pregnancy outcomes of BV patients in pregnancy is comparable to that of oral metronidazole treatment

and the effective rate of treatment is better than oral metronidazole treatment

which is safe and effective and worthy of clinical application.