Objective To investigate the effect of laparoscopic radical D3 radical surgery and total mesocolonectomy（CME）on right colon cancer.Methods The clinical data of 156 patients with colon cancer admitted to a hospital in Leshan City from May 2015 to August 2017 were retrospectively analyzed

of which 65 patients underwent laparoscopic D3 radical surgery（D3 radical surgery group）and 91 patients underwent laparoscopic CME surgery（CME group）.The operation time

intestinal exhaust time

length of hospital stay

intraoperative bleeding volume

postoperative drainage volume

number of lymph node dissection

postoperative complications

and colon cancer recurrence and metastasis were compared between the two groups.Results The operation time

intestinal exhaust time

and length of hospital stay were shorter in the D3 radical surgery group than in the CME group

and the differences were statistically significant（P<0.05）.The intraoperative blood loss

postoperative drainage volume

and lymph node dissection were all less than the CME group

the differences were statistically significant（P <0.05）.The postoperative complication rate of patients in the D3 radical surgery group was6.15%

which was lower than 6.59%in CME patients

but the difference was not statistically significant（P>0.05）.After 2 years of follow-up

the incidence of recurrence and metastasis in the D3 radical surgery group was12.30%（1 liver metastasis in stageⅡ

2 liver metastases

and 1 lung metastasis in stageⅢ;2 cases of local recurrence in stageⅡ

and 2 cases of stageⅢ Local recurrence）was higher than 5.50%in the CME group（2 cases of liver metastasis in stageⅢ;1 case of local recurrence in stageⅡ

2 cases of local recurrence in stageⅢ）

but the difference was not statistically significant（P>0.05）.Conclusion Laparoscopic D3 radical surgery is more effective and safe in treating right colon cancer than CME.It is worthy of clinical application.