Objective To explore the effect of low dose dopamine combined with dobutamine in the treatment of severe pneumonia in children.Methods One hundred children with severe pneumonia in a hospital in Shenyang from March 2017 to March 2019 were selected as the study objects

The children were divided into study group and control group

50 cases in each group.Control group received routine treatment

The children in the study group received low-dose dopamine combined with dobutamine on the basis of the control group.The levels of IL-6

IL-8 and CRP were compared before and after treatment;Before and after treatment

PEF

TEF50%and TPEF/TE were compared between the two groups;The clinical effects of the two groups were compared.Results The total effective rate of the study group was 94.0%

higher than 76.0% of the control group

The difference was statistically significant（P<0.05）.After treatment

The levels of IL-6

IL-8 and CRP in the study group were（52.99±7.82）pg/mL（19.87±3.14）pg/mL and（12.37±2.98）mg/L

which were lower than those in the control group（73.87±8.35）pg/ml

（28.72±3.67）pg/mL and（23.02±6.37）mg/L

The difference was statistically significant（P<0.05）.After treatment

PEF and TEF50%in the study group were（70.38±4.27）mL/s and（69.42±3.35）mL/s respectively

which were lower than those in the control group（78.09±5.42）mL/s and（76.03±3.89）mL/s

The difference was statistically significant（P<0.05）.After treatment

TPEF/TE in the study group was（26.64±3.87）

which was higher than that in the control group（21.32±3.38）

The difference was statistically significant（P<0.05）.Conclusions On the basis of routine treatment

The treatment of severe pneumonia in children with low dose dopamine and dobutamine can achieve ideal results

It can effectively regulate the level of serum inflammatory factors in children

Promote the recovery of children′s lung function

It can be recommended for the treatment of severe pneumonia in children.