Effects of musk-mallow combined with benazepril on chronic glomerulonephritis and its effects on the levels of proteinuria-related indicators in patients
Yan Xue, Zhang Chunhua, Jiang Hongxia. Effects of musk-mallow combined with benazepril on chronic glomerulonephritis and its effects on the levels of proteinuria-related indicators in patients[J]. Health Medicine Research and Practice, 2019,16(6):40-43.
Yan Xue, Zhang Chunhua, Jiang Hongxia. Effects of musk-mallow combined with benazepril on chronic glomerulonephritis and its effects on the levels of proteinuria-related indicators in patients[J]. Health Medicine Research and Practice, 2019,16(6):40-43.DOI:
Objective To investigate the effects of musk-mallow combined with benazepril in the treatment of chronic glomerulonephritis and its effects on the levels of proteinuria-related indicators in patients.Methods Ninety-six patients with chronic glomerulonephritis admitted to a hospital in Liaoning province from June 2018 to April 2019 were selected as the research subjects
and the random number table method was used to divide them into a control group and a study group
with 48 cases in each group.Patients in the control group were orally given benazepril hydrochloride tablets.Patients in the study group were orally given musk-mallow capsules 1 hafter each meal on the basis of the control group.Both groups were treated continuously for 2 months.The clinical efficacy and complications of the two groups were compared
and the levels of 24 hurinary protein quantification(24 h UPQ)
red blood cell(RBC)in urine
serum creatinine(Scr)
blood urea nitrogen(BUN)
and estimated glomerular filtration rate(eGFR)were compared between the two groups.Results The total effective rate of treatment in the study group was 95.83%(46/48)
which was significantly higher than that of 81.25%(39/48)in the control group(P<0.05).Before treatment
there was no significant difference in the levels of 24 hUPQ
RBC in urine
BUN
Scr
and eGFR between the two groups(P>0.05).After treatment
patients in the study group had significantly lower levels of 24 hUPQ
RBC in urine
BUN
and Scr(P<0.05)
as well as significantly higher eGFR level(P<0.05).After treatment
the levels of 24 hUPQ
RBC in urine
BUN
and Scr in the study group was significantly lower than those in the control group(P<0.05)
while the eGFR level in the study group was significantly higher than that in the control group(P<0.05).The incidence of complications in the study group was 6.24%(3/48)
which was significantly lower than the control group′s 18.75%(9/48)(P<0.05).Conclusion Musk-mallow combined with benazepril in the treatment of chronic glomerulonephritis can significantly alleviate the symptoms
improve the renal function of patients with fewer complications