Pan Feng, Shen Yi-cong, Li Zhi-dan. The Efficacy of Rosuvastatin on the Intervention Treatment of Hypertension[J]. Health Medicine Research and Practice, 2015,12(1):63-65.
Pan Feng, Shen Yi-cong, Li Zhi-dan. The Efficacy of Rosuvastatin on the Intervention Treatment of Hypertension[J]. Health Medicine Research and Practice, 2015,12(1):63-65.DOI:
Objective To investigate the efficacy of rosuvastatin on blood lipid and blood pressure in hypertensive patients in the conventional treatment.Method 86 cases of patients with hypertension were randomly divided into an observation group with 41 cases and a control group with 45 cases.Patients in the control group were taken oral irbesartan tablets 150 mg
once a day.Those in the observation group were taken oral rosuvastatin 5mg
once a day
on the basis of the control group.After two weeks
patients in both groups whose blood pressure were higher than 140/90mmHg(1 mmHg=0.133kPa)were added another antihypertensive drug according to their actual conditions.The changes of blood lipid and blood pressure in all the patients were compared after three-month treatment.Results After the treatment
levels of blood pressure
total cholesterol(TC)
triglyceride(TG)
low density lipoprotein cholesterol(LDL-C)in both groups were lower than pretreatment
and the differences were statistically significant(P<0.05);all the indicators from the observation group were lower than the control group and the difference between the two groups was statistically significant(P<0.05).Conclusion The application of rosuvastatin in the conventional treatment of hypertension can enhance the clinical efficacy and improve levels of blood pressure and blood lipid in patients.