In several decades，Sarcopenia has been a focus of medical disciplines. Due to malnutrition and mediators in the liver-muscle axis，sarcopenia is common in patients of end-stage liver disease and is associated with a wide spectrum of adverse outcomes including hepatic decompensation，death and adverse posttransplant outcomes..CT is considered to be a gold standard for assessing loss of muscle mass in patients with end-stage liver disease. Exercise and nutritional intervention prevail as mainstays of treatment. Compared with exercise training，nutrition interventions are targeted and tailored for patients of advanced liver disease. Therefore，this article reviewed the definition，mechanism，diagnosis and nutritional intervention of sarcopenia，in order to provide reference for nutritional intervention of sarcopenia in patients with end-stage liver disease.