Astragalus membranaceus，also known as“the supreme tonic herb”，its function is to tonify the spleen and Qi，raise yang energy，and lift sinking. It is commonly found in classic prescriptions for tonifying the spleen and lung Qi，making it a popular tradi⁃ tional Chinese medicine for Qi tonification in clinical practice. With the deepening of modern research on Astragalus membranaceus，it has been widely used in the treatment of respiratory，digestive，urinary，and blood system diseases，as well as diabetes and its complica⁃ tions. However，there is currently no systematic review of the recent pharmacological research on Astragalus membranaceus. Therefore， this article reviewed recent literature on the basic and clinical research of Astragalus membranaceus，summarizing the research progress of its modern pharmacological effects. The aim was to interpret the traditional understanding of Astragalus membranaceus from the per⁃ spective of modern medicine and provide a reference for its basic research and clinical application.