Objective To explore the effects of enhanced recovery after surgery（ERAS）for postoperative rehabilitation and post-traumatic stress disorder（PTSD）in patients with cardiac surgery under cardiopulmonary bypass（CPB）. Methods From June 2018 to December 2019

320 patients who underwent CPB cardiac surgery were divided into control group and observation group accord⁃ing to chronological order

with 160 cases in each group. The control group received routine cardiac surgery care

while the observation group received ERAS intervention. The postoperative rehabilitation indexes and complications of the two groups were compared

the quality of recovery was evaluated by the 40-item recovery quality score scale（qoR-40）

and the PTSD was evaluated by The PTSD Cheeklist-CivilianVersion（PCL-C）. Results The intraoperative blood loss

plasma dosage

postoperative anesthesia recovery time

first bowel movement time

extubation time

hospital stay and postoperative complication rate of the observation group were lower than those of the control group（P<0.05）. At 48 hours after surgery

the qoR-40 score of the observation group was higher than that of the control group（P<0.05）. At 1 week

1 month

and 3 months after surgery

the PCL-C scores of the observation group were lower than that of the control group（P<0.05）. The positive rate of PTSD symptoms and the detection rate of three major symptoms in the observation group were lower than those in the control group（P<0.05）. Conclusion ERAS conceptual intervention was helpful to reduce the degree of trauma stress response in patients with CPB cardiac surgery

which could promote postoperative rehabilitation

improve the quality of re⁃habilitation

reduce and prevent the occurrence of PTSD.