Asthma is a common chronic inflammatory disease of the airway with the participation of a variety of cells and cellular components. Its acute attack can bring certain challenges to anesthesiologists. If it is not treated correctly in time，it may endanger the lives of patients. In recent years，it has been found that the effect of sevoflurane on asthma is reflected in many aspects of the pathological process of asthma，which is mainly related to inhibiting airway inflammation，promoting airway dilation，inhibiting airway remodeling and so on. In this paper，the relevant experimental studies on the effect of sevoflurane on asthma in recent years and the clinical application of sevoflurane in asthma status are reviewed to provide some theoretical basis for the use of sevoflurance for asthma relief.