Objective To analyze the feasibility of a new type of short-segment intramedullary nailing system for the fixation of a midclavicular fracture model. Methods Twenty-four fresh clavicle specimens from male adults were selected to establish a transverse midclavicular fracture model，and were randomly divided into group A （fixation with an anatomical plate），group B （fixation with the novel intramedullary nail），and group C （fixation with an elastic intramedullary nail），followed by four-point bending testing，torsion testing，and tensile testing in turn. Results In four-point bending testing and torsion testing，the new intramedullary nailing system had significantly better stability than the elastic intramedullary nail （P < 0.05），and showed similar stability to the anatomical plate （P >0.05）. In tensile testing，the stability of the new intramedullary nailing system was significantly better than that of the elastic intramedullary nail （P < 0.05），but worse than that of the anatomical plate （P < 0.05）. Conclusion The new intramedullary nailing system can provide reliable mechanical stability against bending，torsion，and tension in fixing adult midclavicular fractures. It can theoretically meet the treatment requirements for this type of fracture. At the same time，it is simple in operation and minimally invasive，and has the advantage of anti-rotation.