Background Dried ginger with aconite is one of the classic antidote of Zhongjing Jingfang，which is widely used in clinical practice，especially for critically ill patients. Objective To investigate the distribution law and the dose-effect relationship of Ganjiang and Fuzi in Treatise on Febrile Diseases. Methods To analyze the odors of aconite and dried ginger in“Treatise on Febrile Dis-eases”and their syndrome and treatment laws，compatibility characteristics and dose-effect relationship in different prescriptions. Re-sults The top 12（frequency ≥ 2）symptoms in descending order were: Xia Li（8 times），vomiting（7 times），fever（4 times），annoy-ance（4 times），Jueni（4 times），weak pulse（4 times），abdominal pain（2 times），heavy pulse（2 times），dysuria（2 times），cough（2 times），headache（2 times），body pain（2 times）. In Treatise on Febrile Diseases，dried ginger uses 24 squares（times），1 square for ten liang；9 squares for three liang；5 squares for two liang；3 squares；one or two 5 squares；six baht 1 square. Aconite has 23 squares （times），of which six taels are 1 square；one tael is 1 square；three pieces are 2 squares；two pieces are 2 squares；one piece is 17 squares. The combination of the two uses 12 prescriptions to warm the yang and dispel the cold，and to restore the yang to save the evil. Conclusion Dried ginger and aconite have a wide range of clinical applications. Different doses have different effects. When Zhongjing treats diseases，the single dosage of dried ginger and aconite in his prescription，the compatibility relationship，the addition and subtrac-tion according to the syndrome，etc.，attaches great importance to the yang qi of the human body，which is worth learning from.