HE Yuqin, CHEN Dongfeng. New insights into IgG4-related gastrointestinal damage[J]. Journal of Southwest Medical University, 2022,45(1):13-16. DOI: 10.3969/j.issn.2096-3351.2022.01.003.
IgG4-related disease is a multisystem disease caused by autoimmune dysfunction and characterized by chronic inflammation and fibrosis. IgG4-related disease is likely to be an underestimated rare disease, and the incidence of IgG4-related gastrointestinal disease in particular is poorly studied. Until now, there is no relevant expert consensus or guidance for IgG4-related gastrointestinal disease in China. This article gives an overview of IgG4-related disease and reviews clinical features of IgG4-related gastrointestinal disease and advances in the diagnosis and treatment of IgG4-related disease, in order to improve the understanding of the disease in clinicians.