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1. 西南医科大学中西医结合学院,泸州,646000
2. 西南医科大学附属中医医院 老年病科,泸州,646000
纸质出版日期:2021,
网络出版日期:2021-11-20,
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黄小倩, 古远云, 陈, 等. 控糖膳治疗2型糖尿病的临床研究[J]. 西南医科大学学报, 2021,44(6):654-658.
A clinical study of glucose-controlling diet in the treatment of type 2 diabetes[J]. Journal of Southwest Medical University, 2021,44(6):654-658.
黄小倩, 古远云, 陈, 等. 控糖膳治疗2型糖尿病的临床研究[J]. 西南医科大学学报, 2021,44(6):654-658. DOI: 10.3969/j.issn.2096-3351.2021.06.012.
A clinical study of glucose-controlling diet in the treatment of type 2 diabetes[J]. Journal of Southwest Medical University, 2021,44(6):654-658. DOI: 10.3969/j.issn.2096-3351.2021.06.012.
目的通过观察控糖膳治疗2型糖尿病的临床疗效,为其临床应用提供依据。方法将我院就诊的62例2型糖尿病患者,按照随机数字表法,分为观察组和对照组。两组在维持原有降糖方案基础上采用不同饮食,对照组采用普通糖尿病饮食,观察组食用控糖膳(中、晚餐),治疗周期为3个月。对比两组治疗后的临床疗效、症状积分、空腹血糖(fastingbloodglucose,FBG)、口服葡萄糖耐量试验后2h血糖(oralglucosetolerancetest,2h-PG)、糖化血红蛋白(hemoglobina1c,HbA1c)、减/停药率、低血糖不良反应发生情况。结果观察组总有效率87.1%,对照组为77.4%,经卡方检验两组临床疗效相当(P>0.05);临床症状积分观察组明显优于对照组(P<0.05);观察组FBG、2h-PG、HbA1c控制情况均优于对照组(P<0.05);观察组总减/停药率为58.1%,高于对照组(P<0.05);两组均无低血糖不良反应发生。结论控糖膳为低血糖生成指数(glycemicindex,GI)食物,配方符合中医辨证施膳原则,可有效稳定和控制2型糖尿病患者血糖水平,减少/停止使用降糖药,无低血糖不良反应,与普通糖尿病饮食相比,有显著优势。
Objective To observe the clinical efficacy of a glucose-controlling diet in the treatment of type 2 diabetes
and to provide a basis for its clinical application. Methods Sixty-two patients with type 2 diabetes admit⁃ted to our hospital were randomly divided into observation group and control group. In addition to original hypoglyce⁃mic treatment
the control group had a conventional diabetic diet
and the observation group had a glucose-control⁃ling diet (at lunch and dinner). The treatment cycle was 3 months. The two groups were compared in terms of clinical efficacy
symptom score
fasting blood glucose(FBG)
2-hour plasma glucose(2h-PG)after the oral glucose toler⁃ance test
glycosylated hemoglobin(HbA1c),medicine reduction/withdrawal rate
and hypoglycemia incidence after treatment. Results The overall response rate showed no significant difference between the observation group and control group(87.1% vs 77.4%
P>0.05
by the chi-square test). The clinical symptom score of the observation group was significantly better than that of the control group(P<0.05). The observation group showed significantly better FBG
2h-PG
and HbA1c control than the control group(P < 0.05).The overall medicine reduction/with⁃drawal rate was significantly higher in the observation group than in the control group(58.1% vs 0%
P<0.05). No hypoglycemic events occurred in any group. Conclusion The glucose-controlling diet has a low glycemic index
and its formula conforms to the principle of syndrome differentiation-based dieting in traditional Chinese medicine. It can effectively stabilize and control the blood glucose level
reduce the use of hypoglycemic drugs
and cause no hy⁃poglycemic adverse reactions in patients with type 2 diabetes
showing significant advantages over the conventional diabetes diet.
2型糖尿病控糖膳食疗血糖
Type 2 diabetesGlucose-controlling dietDiet therapyBlood glucose
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