医学分子遗传学教学实践研究

徐竞; 易萍

doi:10.3760/cma.j.cn116021-20200801-01242

您当前的位置：

首页 >

文章列表页 >

医学分子遗传学教学实践研究

教学改革 | 更新时间：2023-05-12

- 医学分子遗传学教学实践研究
- Research on the teaching practice of medical molecular genetics
- 中华医学教育探索杂志 2023年22卷第4期页码：540-542
- 作者机构：
  
  重庆医科大学附属第三医院妇产中心，重庆 401120
- 作者简介：
  
  徐竞，Email：xujingzy@sina.com
- 基金信息：
- DOI：10.3760/cma.j.cn116021-20200801-01242
  中图分类号： R715.5
- 纸质出版日期：2023-04-20，
  
  收稿日期：2020-08-01，
扫描看全文
徐竞, 易萍. 医学分子遗传学教学实践研究[J]. 中华医学教育探索杂志, 2023, 22(4): 540-542.

Xu Jing, Yi Ping. Research on the teaching practice of medical molecular genetics[J]. Chinese Journal of Medical Education Research, 2023,22(4):540-542.
徐竞, 易萍. 医学分子遗传学教学实践研究[J]. 中华医学教育探索杂志, 2023, 22(4): 540-542. DOI： 10.3760/cma.j.cn英文已校 202003129徐竞YYT-2022-5修改.

Xu Jing, Yi Ping. Research on the teaching practice of medical molecular genetics[J]. Chinese Journal of Medical Education Research, 2023,22(4):540-542. DOI： 10.3760/cma.j.cn116021-20200801-01242.

摘要

针对医学分子遗传学内容抽象复杂、信息更新迅速、教与学的难度都很高的问题，本研究探讨总结临床医学专业研究生课程和实习生教学中医学分子遗传学的教学方法：夯实基础理论，注重学科融合；引入临床病例，激发主动学习；突出知识更新，鼓励线上查阅；教学科研结合，启发创新思维。结果表明，学生表现出更浓厚的学习兴趣和热情，能更独立和创新地进行思考。对分子遗传学的基础理论和临床应用进行分析，问卷显示课程教学满意度为97%（152/157）。

Abstract

Medical molecular genetics has the complex content and rapidly renewed information

and is difficult to learn and to teach. Therefore

this study explores and summarizes the teaching methods of medical molecular genetics in the postgraduate courses of clinical medicine and in the teaching of interns: paying attention to both basic theory and discipline integration; introducing clinical cases to stimulate the active learning; encouraging online reading to obtain the renewed knowledge; and enlightening the creative thinking through the combination of teaching and research. The results showed that students have more interest and enthusiasm in learning and can think more independently and innovatively. The basic theory and clinical application of molecular genetics have been also analyzed. The questionnaire showed that the teaching satisfaction reaches 97% (152/157).

关键词

医学分子遗传学基因医学教学

Keywords

Medical molecular geneticsGeneMedical teaching

references

Lemire S, Yehl KM, Lu TK. Phage-based applications in synthetic biology [J]. Annu Rev Virol, 2018, 5(1): 453-476. DOI: 10.1146/annurev-virology-092917-043544http://dx.doi.org/10.1146/annurev-virology-092917-043544.

李振刚. 分子遗传学[M]. 4版. 北京：科学出版社， 2014.

Li LL, Cao YX, Zhao FY, et al. Validation and classification of atypical splicing variants associated with osteogenesis imperfecta [J]. Front Genet, 2019, 10: 979. DOI: 10.3389/fgene.2019.00979http://dx.doi.org/10.3389/fgene.2019.00979.

Steiner RD, Basel D. COL1A1/2 osteogenesis imperfecta [M]. GeneReviews®, 2005.

Okubo M, Noguchi S, Hayashi S, et al. Exon skipping induced by nonsense/frameshift mutations in DMD gene results in Becker muscular dystrophy [J]. Hum Genet, 2020, 139(2): 247-255. DOI: 10.1007/s00439-019-02107-4http://dx.doi.org/10.1007/s00439-019-02107-4.

Hagerman RJ, Berry-Kravis E, Hazlett HC, et al. Fragile X syndrome [J]. Nat Rev Dis Primers, 2017, 3: 17065. DOI: 10.1038/nrdp.2017.65http://dx.doi.org/10.1038/nrdp.2017.65.

Ferreira IR, Cunha WDDS, Gomes LHF, et al. A rapid and accurate methylation-sensitive high-resolution melting analysis assay for the diagnosis of Prader Willi and Angelman patients [J]. Mol Genet Genomic Med, 2019, 7(6): e637. DOI: 10.1002/mgg3.637http://dx.doi.org/10.1002/mgg3.637.

Chao A, Lin YH, Yang LY, et al. BRCA1/2 mutation status in patients with metachronous breast and ovarian malignancies: clues towards the implementation of genetic counseling [J]. J Gynecol Oncol, 2020, 31(3): e24. DOI: 10.3802/jgo.2020.31.e24http://dx.doi.org/10.3802/jgo.2020.31.e24.

Fu Y, Liu WJ. Research progress on the laboratory diagnosis for thalassemia-review [J]. Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2018, 26(2): 631-636. DOI: 10.7534/j.issn.1009-2137.2018.02.055http://dx.doi.org/10.7534/j.issn.1009-2137.2018.02.055.

Wu N, Ming X, Xiao J, et al. TBX6 null variants and a common hypomorphic allele in congenital scoliosis [J]. N Engl J Med, 2015, 372(4): 341-350. DOI: 10.1056/NEJMoa1406829http://dx.doi.org/10.1056/NEJMoa1406829.

Weiss LA, Shen YP, Korn JM, et al. Association between microdeletion and microduplication at 16p11.2 and autism [J]. N Engl J Med, 2008, 358(7): 667-675. DOI: 10.1056/NEJMoa075974http://dx.doi.org/10.1056/NEJMoa075974.

Jacquemont S, Reymond A, Zufferey F, et al. Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus [J]. Nature, 2011, 478(7367): 97-102. DOI: 10.1038/nature10406http://dx.doi.org/10.1038/nature10406.

浏览量

下载量

CSCD

文章被引用时，请邮件提醒。

提交

工具集

关联资源

基于医学专业特性对线上教学督导的分析与研究