Objective To investigate the clinical value of ultrasound-guided superficial lymph node biopsy in children.MethodsA total of 195 children with superficial lymphadenectasis were selected and underwent ultrasound-guided superficial lymph node biopsy.Taking the postoperative pathological results as standard

the accurate diagnostic rate of ultrasound-guided biopsy

the sensitivity and specificity of the diagnosis of cervical lymph node malignant lesions

and the sample quality were calculated.According to the immunohistochemistry results

the influence factors of diagnostic accuracy

and the relationship between cervical lymph node lesion and cervical lymph node region were analyzed.Results（1） Among 195children

166 cases were benign diagnosed by biopsy

of which 1 case of lymph node tuberculosis was misdiagnosed

21 cases were malignant

8 cases were not diagnosed

and 1 case of Hodgkin’s lymphoma was missed.Taking postoperative pathological diagnosis as the standard

the sensitivity

specificity

positive predictive value and negative predictive value of ultrasound-guided biopsy in the diagnosis of malignant lesions were 95.5%

100%

100%and 99.4%respectively.None of the 195 children had massive bleeding or other serious complications.（2）The diagnostic accuracy of biopsy was 99.4%for qualified sample

and 75.8%for unqualified sample.The difference was statistically significant（χ

2

=29.5988

P

<

0.05）.The diagnostic accuracy was 99.0%for those with immunohistochemistry and 91.6%for those without immunohistochemistry

and the difference was statistically significant（χ

2

=4.5253

P

<

0.05）.（3）The incidence of cervical lymph node was highest in regionⅡ

malignant was 72.7%and benign was 81.6%.ConclusionUltrasound-guided superficial lymph node biopsy has high diagnostic value

with advantages of simple operation

low price

safety

good tolerance

and so on

which has a promising application.