Neuropathic pain is difficult to treat clinically

which not only affects the patient ’ s quality of life

but even threatens patient’s life.Dorsal root ganglion（DRG） neurons are the main anatomic sites for the occurrence and maintenance of neuropathic pain

and the potassium channels of DRG neurons are closely related to the firing frequency of action potential and the neuronal activities.Ultrasound can act on the ion channels of individual cells in vitro and the ion channels in local tissues in vivo to make them open or close.In this paper

the mechanism and research status of potassium channel as ultrasound target for the treatment of neuropathic pain are reviewed.