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1. 新疆维吾尔自治区克拉玛依市中心医院超声医学科
2. 新疆维吾尔自治区克拉玛依市中心医院健康管理中心
纸质出版日期:2020,
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[1]秦川,魏亚巧,朱小燕.超声射频信号分析评价健康成人颈总动脉结构及功能的研究[J].临床超声医学杂志,2020,22(10):759-763.
QIN Chuan, WEI Yaqiao, ZHU Xiaoyan. Evaluation of common carotid arterial function and structure in healthy adults by ultrasound radio frequency data technology[J]. Journal of Clinical Ultrasound in Medicine, 2020,22(10):759-763.
[1]秦川,魏亚巧,朱小燕.超声射频信号分析评价健康成人颈总动脉结构及功能的研究[J].临床超声医学杂志,2020,22(10):759-763. DOI: 10.16245/j.cnki.issn1008-6978.2020.10.011.
QIN Chuan, WEI Yaqiao, ZHU Xiaoyan. Evaluation of common carotid arterial function and structure in healthy adults by ultrasound radio frequency data technology[J]. Journal of Clinical Ultrasound in Medicine, 2020,22(10):759-763. DOI: 10.16245/j.cnki.issn1008-6978.2020.10.011.
目的应用超声射频信号的血管内-中膜分析技术(QIMT)、血管硬度定量分析技术(QAS)评价健康成人颈总动脉的结构及功能。方法选取360例健康成人
根据年龄分为青年组(20~39岁)、中年组(>39~59岁)和老年组(>59~79岁)
每组均为120例
分别应用QIMT技术测量各组双侧颈总动脉内-中膜厚度(IMT)
QAS技术测量双侧颈总动脉的弹性参数
包括扩张系数(DC)、顺应性系数(CC)、僵硬度指数(α、β)、脉搏波传导速度(PWV)。获取受检者一般资料和实验室生化指标
包括:空腹血糖(FBG)、血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL-C)和低密度脂蛋白(LDL-C)
比较上述各参数在颈总动脉不同侧别、不同性别及不同年龄间的差异。分析颈总动脉结构及弹性功能参数与一般资料、实验室指标的相关性。结果①颈总动脉左、右两侧间的QIMT和QAS参数比较
差异均无统计学意义。②男性颈总动脉DC高于女性
差异有统计学意义(P<0.05)。③青年组、中年组、老年组的IMT依次增厚
DC依次减小
差异均有统计学意义(均P<0.05);与青年组比较
中年组和老年组的CC减低
α、β及PWV增加
差异均有统计学意义(均P<0.05)。相关性分析结果显示:IMT与LDL呈正相关(r=0.396
P<0.05);DC与HDL、LDL均相关(r=0.452、-0.354
均P<0.05);CC与年龄、HDL、LDL均相关(r=-0.378、0.422、-0.382
均P<0.05)
PWV与HDL、LDL均相关(r=-0.467、0.353
均P<0.05)。结论应用超声射频信号技术可发现健康成人颈总动脉的结构及功能随年龄、性别变化存在差异。
Objective To evaluate common carotid arterial structure and function in healthy adults by quality intimamedia thickness(QIMT)and quantitative artery stiffness(QAS).Methods A total of 360 subjects were divided into 3 groups according to age: young group(20~39 years old)
middle-age group(>39~59 years old)and aged group(>59~79 years old)
120 subjects in each group. The bilateral common carotids arterial intima-media thickness(IMT)and the elasticity parameters were respectively measured by QIMT and QAS. The distention coefficient(DC)
the compliance coefficient(CC)
the stiffness parameter(α
β)and the pulse wave velocity(PWV)were analyzed. General information and laboratory biochemical indicators were obtained
including fasting blood glucose(FBG)
serum total cholesterol(TC)
triglyceride(TG)
high-density lipoprotein(HDL-C)and low-density lipoprotein(LDL-C). The results of parameters among bilateral carotids
different genders and different ages were compared.Results (1)There were no statistically significant differences in the IMT
DC
CC
α
β and PWV of bilateral common carotids.(2) The DC of male was higher than that of female
and there were statistically significant differences(P<0.05).(3) The IMT was increased with DC values decreasing from young group to middle-age group and aged group. Compared with young group
the CC was decreased with the α
β and PWV values increasing in middle-age group and aged group(all P<0.05).Correlation analysis showed that IMT was positively correlated with LDL(r=0.396
P<0.05).DC was correlated with HDL and LDL(r=0.452
-0.354
all P<0.05).CC was correlated with age
HDL and LDL(r=-0.378
0.422
-0.382
all P<0.05)
PWV was correlated with HDL and LDL(r=-0.467
0.353
all P<0.05).Conclusion Age and gender have influences in structure and function of common carotid artery in healthy adults.
超声检查多普勒彩色颈总动脉弹性内-中膜厚度
UltrasonographyDopplercolorCarotid arteryElasticityIntima-media thickness
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