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广东省佛山市第一人民医院超声诊疗中心
纸质出版日期:2020,
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[1]伍卫如,陈炯垣.经腹超声与X线平片预测新生儿坏死性小肠结肠炎临床转归的对比研究[J].临床超声医学杂志,2020,22(09):669-674.
WU Weiru, CHEN Jiongyuan. Comparative study of transabdominal ultrasonography and X-ray in predicting the clinical outcome of neonatal necrotizing enterocolitis[J]. Journal of Clinical Ultrasound in Medicine, 2020,22(9):669-674.
[1]伍卫如,陈炯垣.经腹超声与X线平片预测新生儿坏死性小肠结肠炎临床转归的对比研究[J].临床超声医学杂志,2020,22(09):669-674. DOI: 10.16245/j.cnki.issn1008-6978.2020.09.010.
WU Weiru, CHEN Jiongyuan. Comparative study of transabdominal ultrasonography and X-ray in predicting the clinical outcome of neonatal necrotizing enterocolitis[J]. Journal of Clinical Ultrasound in Medicine, 2020,22(9):669-674. DOI: 10.16245/j.cnki.issn1008-6978.2020.09.010.
目的比较经腹超声与X线平片在协助诊断新生儿坏死性小肠结肠炎(NEC)和预测临床转归中的应用价值。方法选取我院儿科收治的80例NEC患儿
根据修正Bell-NEC分级诊断标准将患儿分为修正Bell-NEC分级ⅠA、ⅠB级39例(A组)和修正Bell-NEC分级ⅡA级以上41例(B组);另根据临床转归分为转归良好组50例(内科保守治疗)和转归不良组30例(手术治疗或死亡)。各组均行经腹超声和X线平片检查
比较两种影像学检查结果。应用Logistic回归分析筛选影响NEC患儿临床转归不良的X线平片和经腹超声表现;绘制受试者工作特征(ROC)曲线评估X线平片和经腹超声对NEC患儿转归不良的预测价值。结果 B组经腹超声对肠管扩张和门静脉积气的检出率分别为58.54%(24/41)和36.59%(15/41)
高于X线平片的36.59%(15/41)、17.07%(7/41)
差异均有统计学意义(均P<0.05)。转归不良组X线平片对腹腔游离气体、肠壁积气、门静脉积气、肠管扩张的检出率分别为13.33%(4/30)、16.67%(5/30)、20.00%(6/30)、50.00%(15/30)
高于转归良好组的2.00%(1/50)、2.00%(1/50)、2.00%(1/50)、24.00%(12/50)
差异均有统计学意义(均P<0.05);转归不良组经腹超声对腹腔游离气体、腹腔积液、肠壁增厚、肠管扩张检出率分别为16.67%(5/30)、50.00%(15/30)、53.33%(16/30)、50.00%(15/30)
高于转归良好组的2.00%(1/50)、24.00%(12/50)、24.00%(12/50)、32.00%(16/50)
差异均有统计学意义(均P<0.05)。Logistic回归分析显示
经腹超声检出腹腔游离气体、腹腔积液、肠壁增厚
X线平片检出肠管扩张、腹腔游离气体均是NEC患儿临床转归不良的危险因素(均P<0.05)。ROC曲线分析显示
经腹超声和X线平片预测NEC患儿转归不良的曲线下面积分别为0.829(95%可信区间:0.730~0.927)和0.702(95%可信区间:0.581~0.823)
差异有统计学意义(Z=2.036
P<0.05)。结论与X线平片比较
经腹超声对NEC患儿肠管扩张、门静脉积气的检出率更高
可观察NEC患儿肠道的细微变化
在早期NEC诊断和临床转归预测方面更具优势。
Objective To compare the application value of transabdominal ultrasonography and X-ray in assistingdiagnosis and predicting clinical outcome of neonatal necrotizing enterocolitis(NEC).Methods Eighty NEC children wereadmitted to our hospital were selected.According to the revised Bell-NEC classification standard
they were divided into gradeⅠA
ⅠB 39 cases(group A)and higher than grade ⅡA 41 cases(group B).Otherwise
according to the clinical outcome
the80 children were divided into good outcome group(improved after conservative treatment in internal medicine
50 cases)andpoor outcome group(operation or death
30 cases).All the children were examined by transabdominal ultrasonography and X-ray
and the results of the two methods were compared.The manifestations of X-ray and transabdominal ultrasonography that affectedthe clinical outcome of NEC children were analyzed by Logistic regression.The receiver operating characteristic(ROC)curve wasdrawn to evaluate the predictive value of the X-ray and transabdominal ultrasonography for the poor outcome of NEC children.Results The detection rate of abdominal ultrasonography for intestinal dilatation and portal venous gas in the group B were58.54%(24/41)and 36.59%(15/41)
which were higher than those in the group A with 36.59%(15/41)and 17.07%(7/41)
there were significant differences(both P<0.05). The detection rate of abdominal free gas
intestinal wall pneumatosis
portalvenous gas and intestinal dilatation by X-ray in the poor outcome group were 13.33%(4/30)
16.67%(5/30)
20.00%(6/30)and50.00%(15/30)
which were higher than those in the good outcome group with 2.00%(1/50)
2.00%(1/50)
2.00%(1/50)
24.00%(12/50)
there were significant differences(all P<0.05).The detection rate of abdominal free gas
peritoneal effusion
intestinal wall thickening
intestinal dilatation by abdominal ultrasonography were 16.67%(5/30)
50.00%(15/30)
53.33%(16/30)
50.00%(15/30)
which were higher than those in the good outcome group with 2.00%(1/50)
24.00%(12/50)
24.00%(12/50)
32.00%(16/50)
there were significant differences(all P<0.05).The results of Logistic regression analysis showed that abdominalfree gas
peritoneal effusion and intestinal wall thickening detected by abdominal ultrasonography
and intestinal dilatation andabdominal free gas detected by X-ray were the risk factors of poor clinical outcome of NEC children(all P<0.05).ROC curveshowed that the area under the curve of transabdominal ultrasonography and X-ray plain film in predicting the poor outcome ofNEC were 0.829(95%CI:0.730~0.927)and 0.702(95%CI:0.581~0.823)
respectively
and the difference was statisticallysignificant(Z=2.036
P<0.05).Conclusion Compared with X-ray
transabdominal ultrasonography has higher detection rate forintestinal dilatation and portal vehous gas in NEC children.It can detect the subtle changes in the intestinal tract of children withNEC
which has higer application value in early diagnosis and clinical prognosis prediction of NEC.
超声检查经腹X线平片坏死性小肠结肠炎新生儿临床转归
UltrasonographytransabdominalX-rayNecrotizing enterocolitisneonatalClinical outcome
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