XIE Yingdong, XU Chaoli, YANG Bin, et al. Value of time-intensity curve of contrast-enhanced ultrasound in early diagnosis of cervical cancer[J]. Journal of Clinical Ultrasound in Medicine, 2020,22(8):626-628.
XIE Yingdong, XU Chaoli, YANG Bin, et al. Value of time-intensity curve of contrast-enhanced ultrasound in early diagnosis of cervical cancer[J]. Journal of Clinical Ultrasound in Medicine, 2020,22(8):626-628. DOI: 10.16245/j.cnki.issn1008-6978.2020.08.024.
ObjectiveTo investigate the clinical value of time-intensity curve of contrast-enhanced ultrasound inearly diagnosis of cervical cancer.MethodsForty patients with early cervical cancer(T1 stage and T2 stage)confirmed bybiopsy or surgical pathology(cervical cancer group)and 65 patients with benign tumor(benign tumor group)were enrolled.Allpatients were examined by transvaginal ultrasound and contrast-enhanced ultrasound.The parameters of time-intensity curveincluding peak time of arrival(TTP)
peak intensity of enhancement(PI)
maximum peak intensity ratio(PI/PIc)
area under thecurve(AUCTC)and mean transit time(MTT)were analyzed quantitatively.The differences between the two groups were compared.ResultsThe shorter TTP
stronger PI
and higher PI/PIc were significantly observed in cervical cancer group than those inbenign tumor group(all P<0.05). However
the AUCTCand MTT were not significantly different between the two groups.ConclusionThe time-intensity curve of contrast-enhanced ultrasound can provide the basis for the diagnosis of earlycervical cancer.