Objective To explore the correlation between hemophilic early arthropathy detection with ultrasound in China（HEAD-US-C） score and the clinical function score in hemophiliacs joints.Methods A total of 240 knee

elbow and ankle joints of 40 male hemophilia patients were evaluated by HEAD-US-C score

the joints ’ function was evaluated by hemophilia joint health scores（HJHS） 2.1 and the functional independence score for haemophilia（FISH）.The correlation between HEAD-US-Cscore and HJHS score

FISH score were analyzed.According to the type of deficiency of coagulation factors

40 hemophilia patients were divided into type A（n=32） and type B（n=8）

then they were to be analyzed whether there were differences among different types of hemophilia patients in HEAD-US-C score

HJHS score and FISH score.Results In the 240 joints of 40 patients

HEAD-US-C score was 22.50（8.00

30.50）

HJHS score was 31.50（15.50

46.75）

and FISH score was 27.00（21.50

32.00）.There were no significant differences in different types of hemophilia patients in HEAD-US-C score

HJHS score and FISH score.There was a positive correlation between HEAD-US-C score and HJHS score（r=0.884

P<0.001）

and a negative correlation between HEAD-US-C score and FISH score（r=-0.825

P<0.001） in 40 hemophilia patients.Conclusion HEAD-US-C score has a good correlation with HJHS score and FISH score

and ultrasound can provide more objective evaluation of joint injury.