Objective To evaluate the feasibility and clinical value of pulmonary lesions and prognosis in neonatal respiratory distress syndrome（NRDS） with pulmonary ultrasound score.Methods A total of 120 neonates with NRDS were selected and treated with mechanical ventilation and pulmonary surfactant.Before and after treatment

lung ultrasound examination was performed and the results of ultrasonic examination of lung lesions were scored.At the same time

compared with the results of chest X-ray examination.Results Ninety of the 120 children were clinically diagnosed as NRDS

and the remaining 30 were temporary respiratory enhancement.Taken the clinical comprehensive diagnosis results as standard

the sensitivity

specificity and accuracy of ultrasound in the diagnosis of NRDS were 95.56%

96.67%

and 95.83%

respectively which were higher than those of X-ray（86.67%

80.00%

85.00%）

the differences were statistically significant（all P<0.05）.The consistency of ultrasound and clinical diagnosis was good（Kappa=0.789）.The pulmonary ultrasound scores of neonates before treatment was lower than that of temporary respiratory enhancement neonates

the differences was statistically significant（P<0.05）

while the pulmonary ultrasound scores of NRDS neonates after treatment was higher than that of before treatment

the differences was statistically significant（P<0.05）.Conclusion Lung ultrasound can detect NRDS more sensitively and accurately

and the lung ultrasound scores can be used to evaluate the degree and prognosis of pulmonary lesions in neonates

which has a good clinical value.