三维斑点追踪成像诊断静息状态下非心肌梗死患者冠状动脉重度狭窄的价值

刘雅菲; 谭宇; 曾赛群; 高慧萍

doi:10.16245/j.cnki.issn1008-6978.2020.05.008

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三维斑点追踪成像诊断静息状态下非心肌梗死患者冠状动脉重度狭窄的价值

临床研究 | 更新时间：2021-10-08

- 三维斑点追踪成像诊断静息状态下非心肌梗死患者冠状动脉重度狭窄的价值
- Value of three-dimensional speckle tracking imaging in diagnosis of severe multi-vessel coronary artery stenosis of non-myocardial infarction in resting state
- 临床超声医学杂志 2020年22卷第5期页码：344-348
- 作者机构：
  
  湖南省株洲市中心医院超声科
- 作者简介：
- 基金信息：
- DOI：10.16245/j.cnki.issn1008-6978.2020.05.008
  中图分类号： R542.22;R445.1
- 纸质出版日期：2020，
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[1]刘雅菲,谭宇,曾赛群,高慧萍.三维斑点追踪成像诊断静息状态下非心肌梗死患者冠状动脉重度狭窄的价值[J].临床超声医学杂志,2020,22(05):344-348.

LIU Yafei, TAN Yu, ZENG Saiqun, et al. Value of three-dimensional speckle tracking imaging in diagnosis of severe multi-vessel coronary artery stenosis of non-myocardial infarction in resting state[J]. Journal of Clinical Ultrasound in Medicine, 2020,22(5):344-348.
[1]刘雅菲,谭宇,曾赛群,高慧萍.三维斑点追踪成像诊断静息状态下非心肌梗死患者冠状动脉重度狭窄的价值[J].临床超声医学杂志,2020,22(05):344-348. DOI： 10.16245/j.cnki.issn1008-6978.2020.05.008.

LIU Yafei, TAN Yu, ZENG Saiqun, et al. Value of three-dimensional speckle tracking imaging in diagnosis of severe multi-vessel coronary artery stenosis of non-myocardial infarction in resting state[J]. Journal of Clinical Ultrasound in Medicine, 2020,22(5):344-348. DOI： 10.16245/j.cnki.issn1008-6978.2020.05.008.

摘要

目的探讨三维斑点追踪成像（3D-STI）诊断静息状态下非心肌梗死患者冠状动脉多支重度狭窄的应用价值。方法选取我院行冠状动脉造影的100例疑似冠状动脉粥样硬化性心脏病患者

根据冠状动脉造影的结果分为多支重度狭窄组（40例）、单支重度狭窄组（30例）及对照组（30例）。所有患者应用3D-STI技术测量静息状态下的左室整体纵向应变（3D-GLS）、圆周应变（3D-GCS）、面积应变（3D-GAS）和径向应变（3D-GRS）

比较各组上述参数的差异。绘制受试者工作特征（ROC）曲线分析3D-STI各参数诊断冠状动脉多支重度狭窄的价值。结果多支重度狭窄组和单支重度狭窄组3D-GLS、3D-GCS、3D-GAS、3D-GRS均明显低于对照组

多支重度狭窄组3D-GLS、3D-GAS均明显低于单支重度狭窄组

差异均有统计学意义（均P<0.05）。3D-GLS、3D-GAS预测冠状动脉多支重度狭窄的ROC曲线下面积分别为0.780、0.770

当3D-GLS截断值为-12%时

其敏感性为85.1%;当3D-GAS截断值为-21%时

其特异性为80.2%;3D-GLS与3D-GCS、3D-GAS、3D-GRS任一指标联合应用

其诊断冠状动脉多支重度狭窄的敏感性均较单一指标高。结论 3D-STI对静息状态下非心肌梗死患者冠状动脉多支重度狭窄有一定的诊断价值

3D-GLS、3D-GAS可作为筛查冠状动脉多支重度狭窄较为有效的诊断指标。

Abstract

Objective To investigate the value of three-dimensional speckle tracking imaging（3 D-STI） in the diagnosis of severe multi-vessel coronary artery stenosis of non-myocardial infarction in resting state.Methods A total of 100 patients with suspected coronary heart disease who underwent coronary angiography were selected as the research objects in our hospital.The patients were divided into severe multi-vessel stenosis group（40 cases）

severe single-vessel stenosis group（30 cases） and control group（30 cases） according to the results of coronary angiography.3 D-STI technology was used to measure the global longitudinal strain（3 D-GLS）

global circumferential strain（3 D-GCS）

global area strain（3 D-GAS） and global radial strain（3 D-GRS） of the left ventricle at rest.The receiver operating characteristic（ROC） curve was used to analyze the value of3 D-STI in the diagnosis of severe multi-vessel coronary artery stenosis.Results The 3 D-GLS

3 D-GCS

3 D-GAS

3 D-GRS of severe multi-vessel stenosis group and severe single-vessel stenosis group were significantly lower than those of control group（all P<0.05）.The 3 D-GLS and 3 D-GAS of severe multi-vessel stenosis group were significantly lower than those of severe single-vessel stenosis group（both P<0.05）.The area under the ROC curve predicted by 3 D-GLS for multiple severe stenosis of coronary artery was 0.780

and the sensitivity was 85.1% when the cutoff value was-12%.The area under the ROC curve predicted by 3 D-GAS for multiple severe stenosis of coronary artery was 0.770

and the specificity was 80.2%

when the cutoff value was-21%.When 3 D-GLS was used in parallel with any of the indicators of 3 D-GCS

3 D-GAS and 3 D-GRS

the sensitivity of diagnosis of severe multi-vessel coronary artery stenosis was higher than that of single indicator.Conclusion 3 D-STI has certain diagnostic value for severe multi-vessel coronary artery stenosis of non-myocardial infarction at rest

3 D-GLS and 3 DGAS can be used as more effective diagnostic indicators for severe multi-vessel coronary artery stenosis.

关键词

斑点追踪成像三维冠状动脉狭窄心室功能左整体应变

Keywords

Speckle tracking imagingthree-dimensionalCoronary artery stenosisVentricular functionleftGlobal strain

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