Objective To investigate the value of myocardial contrast echocardiography and two-dimensional speckle tracking imaging in the evaluation of early left ventricular recovery after percutaneous coronary intervention（PCI） in patients with coronary chronic total occlusion（CTO）.Methods A total of 39 patients with CTO lesions planned for PCI revascularization were enrolled as the experimental group

and 39 subjects with normal coronary angiography and age and sex matched as control group

conventional two-dimensional echocardiography

two-dimensional speckle tracking imaging and myocardial contrast echocardiography were performed before operation

experimental group underwent ultrasonography within 72 h post-PCI revascularization

the left and right ventricular function parameters before and after the operation were compared.According to the different coronary vessels opened

the experimental group were divided into three subgroups:the left anterior descending branch group（16 cases）

the left circumflex branch group（4 cases） and the right coronary artery group（19 cases）.The regional myocardial perfusion and regional myocardial longitudinal strain（RLS） before and after surgery were compared.Results The global longitudinal strain（GLS）

the peak signal intensity of the plateau phase（A）

the slope of curve in each myocardial segment（β）

and the regional myocardial blood flow per second（A·β） in CTO group were lower than those of control group while the myocardial perfusion score index（PSI） was higher before PCI

and the differences were statistically significant（all P<0.05）.In the experimental group

there were no statistically significant differences in the traditional left ventricular function parameters compared with those before PCI.The post-PCI PSI was significantly lower than that of pre-PCI

the GLS

A

β

A·β were significantly increased compared with pre-PCI

the differences were statistically significant（all P<0.05）.Among the three subgroups of CTO patients

the RLS

PSI

A

β

A·β of each coronary artery donated area were significantly improved compared with the pre-PCI（all P<0.05）.Conclusion Both myocardial contrast echocardiography and twodimensional speckle tracking imaging can early and quantitatively evaluate the improvement of left ventricular global and local myocardial perfusion and myocardial motor function in CTO patients after PCI revascularization.