早期类风湿性关节炎手功能障碍与关节内炎症的相关性分析

徐华军; 陈士芳; 张惠美; 施林枫

doi:10.16245/j.cnki.issn1008-6978.2020.01.022

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早期类风湿性关节炎手功能障碍与关节内炎症的相关性分析

经验交流 | 更新时间：2021-10-08

- 早期类风湿性关节炎手功能障碍与关节内炎症的相关性分析
- Correlation analysis of articular inflammations and hand dysfunction in active stage of early rheumatoid arthritis
- 临床超声医学杂志 2020年22卷第1期页码：58-60
- 作者机构：
  
  1. 浙江大学湖州医院湖州市中心医院超声科
  2. 浙江大学湖州医院湖州市中心医院风湿免疫科
  3. 浙江大学湖州医院湖州市中心医院放射科
- 作者简介：
- 基金信息：
  
  浙江省湖州市公益性应用研究项目（2017GYB25、2018GYB68）
- DOI：10.16245/j.cnki.issn1008-6978.2020.01.022
  中图分类号： R445.1;R593.22
- 纸质出版日期：2020，
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[1]徐华军,陈士芳,张惠美,施林枫.早期类风湿性关节炎手功能障碍与关节内炎症的相关性分析[J].临床超声医学杂志,2020,22(01):58-60.

XU Huajun, CHEN Shifang, ZHANG Huimei, et al. Correlation analysis of articular inflammations and hand dysfunction in active stage of early rheumatoid arthritis[J]. Journal of Clinical Ultrasound in Medicine, 2020,22(1):58-60.
[1]徐华军,陈士芳,张惠美,施林枫.早期类风湿性关节炎手功能障碍与关节内炎症的相关性分析[J].临床超声医学杂志,2020,22(01):58-60. DOI： 10.16245/j.cnki.issn1008-6978.2020.01.022.

XU Huajun, CHEN Shifang, ZHANG Huimei, et al. Correlation analysis of articular inflammations and hand dysfunction in active stage of early rheumatoid arthritis[J]. Journal of Clinical Ultrasound in Medicine, 2020,22(1):58-60. DOI： 10.16245/j.cnki.issn1008-6978.2020.01.022.

摘要

目的探讨早期类风湿性关节炎（RA）手功能障碍与关节内炎症之间的相关性。方法回顾性分析63例早期RA伴手功能障碍患者的临床及超声检查资料

分析手功能障碍评分、晨僵视觉评分（MS-VAS）与关节内滑膜增生、滑膜炎、腱鞘炎、关节腔积液及炎症总评分之间的相关性。结果①关节内炎症与手功能障碍的相关性:滑膜增生、滑膜炎与手功能障碍均呈正相关（rs=0.46、0.51

P=0.010、0.003）;腱鞘炎、关节腔积液与手功能障碍均无相关（r

=0.29、0.12

P=0.120、0.160）;关节内炎症总评分与手功能障碍呈正相关（r

=0.53

P=0.002）。②关节内炎症与MS-VAS的相关性:滑膜增生、滑膜炎与MS-VAS均无相关（r

=0.28、0.35

P=0.140、0.060）;腱鞘炎与MS-VAS呈正相关（r

=0.39

P=0.030）;关节腔积液与MS-VAS无相关（r

=0.16

P=0.320）;关节内炎症总评分与MS-VAS呈正相关（r

=0.47

P=0.008）。结论早期RA患者手功能障碍与关节内滑膜炎症相关

晨僵则与腱鞘炎相关

超声提示滑膜炎、腱鞘炎能更加全面地反映早期RA手腕部关节功能。

Abstract

ObjectiveTo explore the correlation between articular inflammations and hand dysfunction in early rheumatoid arthritis.MethodsThe clinical and ultrasond information of 63 early RA patients with hand dysfunction were analyzed

then the relationships among the signals of functional impairment（SOFI）scores

morning stiffness visual analogue scale（MS-VAS）scores

and the ultrasound scores of articular synovitis

synovial hyperplasia

effusion

tenosynovitis and the sum of articular inflammation.Results①The correlation between articular inflammation and SOFI:the articular synovial hyperplasia and synovitis were significantly correlated with SOFI（r

=0.46

0.51

P=0.010

0.003）

tenosynovitis and joint effusion were not significantly correlated with SOFI（r

=0.29

0.12

P=0.120

0.160）

the total ultrasound articular inflammation scores was significantly correlated with SOFI（r

=0.53

P=0.002）. ② The correlation between artidcular inflammation and MS-VAS:the articular synovial hyperplasia and synovitis were not significantly correlated with MS-VAS（r

=0.28

0.35

P=0.140

0.060）

the tenosynovitis was significantly correlated with MS-VAS（r

=0.39

P=0.030）

the joint effusion was not significantly correlated with MS-VAS（r

=0.16

P=0.320）

the total ultrasound articular inflammation scores was significantly correlated with MS-VAS（r

=0.47

P=0.008）.ConclusionThe articular synovitis is correlated with hand dysfunction

and morning stiffness is correlated with tenosynovitis

the combined articular synovitis with tenosynovitis found by ultrasound can reflect the severity of hand dysfunction in early-stage RA patients.

关键词

类风湿性关节炎早期手功能障碍晨僵滑膜炎腱鞘炎

Keywords

Rheumatoid arthritisearlyHand dysfunctionMorning stiffnessSynovitisTenosynovitis

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