OBJECTIVE: To investigate the intervention of irrational medical orders in inpatient pharmacy of the hospital

so as to provide reference for rational drug use in clinical psychiatry. METHODS: Intervention records of irrational medical orders in the inpatient pharmacy of the hospital from 2020 to 2021 were collected

and the types of irrational medical orders and intervention results were statistically analyzed. RESULTS: A total of 4 090 irrational medical orders were recorded

and the types were distributed as inappropriate usage and dosage

repeated administration and improper route of administration

among which inappropriate usage and dosage and repeated administration accounted for 23.18%（948 irrational medical orders） and 26.58%（1 087 irrational medical orders）

respectively. Among all the irrational medication orders

3 920（95.84%） pharmacists’ intervention suggestions were adopted by clinicians. The adoption rate of intervention suggestions in the medical medical orders of repeated administration was 99.82%（1 085/1 087）

while the adoption rate of intervention suggestions in the medical orders of contraindication population was only 57.52%（88/153）. CONCLUSIONS: The review and intervention of irrational medical orders by pharmacists in psychiatric hospitals can improve the safety

effectiveness and rationality of medication for inpatients.