OBJECTIVE: To investigate the application of aconiti lateralis radix praeparata

and to analyze the common dosage of aconiti lateralis radix praeparata and the proportion of off-label use compared with the Chinese Pharmacopoeia: Part I（hereinafter referred to as “pharmacopoeia”）. METHODS: Retrospective analysis method was used to count all traditional Chinese medicine prescriptions of aconiti lateralis radix praeparata in the hospital from 2020 to 2021. Gender

age

number of traditional Chinese medicine used in each prescription

method

dose of aconiti lateralis radix praeparata

commonly used compatibility

and commonly used syndrome types were statistically analyzed. RESULTS: A total of 15 882 prescriptions containing aconiti lateralis radix praeparata were included. Most of the patients were females. The prescriptions with the dose range of 3 to 15 g accounted for 94.55%（15 016 prescriptions） of the total prescriptions. The number of traditional Chinese medicine in a single prescription was mainly 7 to 15

totally 11 724 prescriptions（73.82%）. There were 9 308 prescriptions（58.61%） with 1 to 7 doses prescribed in a single prescription

and 15 638 prescriptions（98.46%） with 30 or fewer doses prescribed in a single prescription. The most frequently used traditional Chinese medicine in combination with aconiti lateralis radix praeparata was angelicae sinensis. CONCLUSIONS: The dosage of aconiti lateralis radix praeparata in the traditional Chinese medicine prescriptions of the hospital was generally in line with the provisions of the pharmacopoeia

and there was no record for use of raw aconiti lateralis radix praeparata. Aconiti lateralis radix praeparata is often used in combination with other medicinal materials.