OBJECTIVE: To probe into the clinical effects of Huanshao capsules combined with tamsulosin hydrochloride in the treatment of premature ejaculation of spleen and kidney yang deficiency type. METHODS: Totally 120 patients with premature ejaculation of spleen and kidney yang deficiency type admitted into the hospital from Jun. 2019 to May 2020 were extracted to be divided into the tamsulosin hydrochloride group

Huanshao capsules group and combination group via the random number table method

with 40 cases in each group. Tamsulosin hydrochloride group was treated with tamsulosin hydrochloride

0.2 mg for once

qd. Huanshao capsules group received Huanshao capsules

5 capsules for once

bid. Combination group was given Huanshao capsule combined with tamsulosin hydrochloride

for 30 d. The efficacy

intravaginal ejaculation latency time（IELT）

Chinese index of sexual function for premature ejaculation（CIPE）

incidence of adverse reactions and sexual satisfaction of both spouses were compared among three groups. RESULTS: The total effective rate of the combination group was 90.00%（36/40）

significantly higher than 67.50%（27/40） of the tamsulosin hydrochloride group and 70.00%（28/40） of the Huanshao capsules group

the differences were statistically significant（P<0.05）. After treatment

the IELT of three groups was longer than that before treatment

and the CIPE was higher than that before treatment

the differences were statistically significant（P<0.05）;the IELT of the combination group was significantly longer than that of the tamsulosin hydrochloride group and the Huanshao capsules group

and the CIPE of the combination group was significantly higher than that of the tamsulosin hydrochloride group and the Huanshao capsules group

the differences were statistically significant（P<0.05）. The incidence of adverse drug reactions in the combination group and Huanshao capsules group were respectively 2.50%（1/40） and 0（0/40）

lower than 20.00%（8/40） in the tamsulosin hydrochloride group

the differences were statistically significant（P<0.05）. The satisfaction of patients in the combination group was 90.00%（36/40）

significantly higher than that in the tamsulosin hydrochloride group（62.50%

25/40） and Huanshao capsule group（67.50%

27/40）

with statistically significant differences（P<0.05）. CONCLUSIONS: The efficacy of Huanshao capsules combined with tamsulosin hydrochloride in the treatment of premature ejaculation of spleen and kidney yang deficiency type is significant

which can prolong IELT

improve CIPE and sexual satisfaction of both spouses

with fewer adverse drug reactions.