HAN Ning, CUI Xiaozheng. Effects of Xuebijing Injection on Myocardial Injury Markers and Inflammatory Indicators in Patients with Sepsis Complicated with Myocardial Injury[J]. 2022,22(6):719-721.
HAN Ning, CUI Xiaozheng. Effects of Xuebijing Injection on Myocardial Injury Markers and Inflammatory Indicators in Patients with Sepsis Complicated with Myocardial Injury[J]. 2022,22(6):719-721. DOI: 10.14009/j.issn.1672-2124.2022.06.019.
OBJECTIVE: To probe into the effects of Xuebijing injection on myocardial injury markers and inflammatory indicators in patients with sepsis complicated with myocardial injury. METHODS: By retrospective analysis
36 patients with sepsis complicated with myocardial injury admitted into the department of intensive care medicine in Beijing Changping District Integrated Chinese and Western Medicine Hospital from Jun. 2018 to Oct. 2021 were extract to be divided into the control group and the control group according to different treatment methods
with 18 cases in each group. The control group was treated with conventional western medicine
while the observation group received Xuebijing injection on the basis of the control group. The improvement of myocardial injury markers [troponin I(cTnI)
creatine kinase isoenzyme(CK-MB)]
N-terminal pro-brain natriuretic peptide(NT-proBNP) and inflammatory indicators [procalcitonin(PCT)
C-reactive protein(CRP) and white blood cell count(WBC)] were compared between two groups. RESULTS: After treatment of 10 d
the improvement of indicators in the observation group was better than that in the control group.(1) The levels of myocardial injury markers(cTnI
CK-MB) and NT-proBNP in the observation group after treatment were lower than those in the control group
the differences were statistically significant(P<0.05).(2) The levels of inflammatory indicators(PCT
CRP and WBC) in the observation group after treatment were lower than those in the control group
with statistically significant differences(P<0.05). CONCLUSIONS: Xuebijing injection is beneficial to improve the levels of myocardial injury markers and reduce the levels of inflammatory indicators in patients with sepsis complicated with myocardial injury.