OBJECTIVE: To explore the mode of inpatient pharmaceutical care for patients with acute pulmonary embolism and standardize the rational application of anticoagulant drugs. METHODS: Patients with acute pulmonary embolism admitted into Zhengzhou Central Hospital Affiliated to Zhengzhou University from Oct. 2020 to Jul. 2021 were selected as the subjects. Among them

patients from Oct. 2020 to May 2021 did not receive inpatient pharmaceutical care mode for anticoagulation therapy. The problems of anticoagulation regimens were evaluated

the main factors affecting the rationality of anticoagulation therapy were clarified by using the Plato method

and the Inpatient Pharmaceutical Care Mode for Anticoagulation Therapy in Patients with Acute Pulmonary Embolism was established. Patients from Jun. to Jul. 2021 were monitored according to the mode

and the rationality of anticoagulation therapy before and after the establishment of the mode was compared to standardize the rational application of anticoagulant drugs in patients with acute pulmonary embolism. RESULTS: Inappropriate drug usage and dosage

no effective overlap treatment

and repeated medication were the main factors affecting the rational application of anticoagulant drugs. After implementation of inpatient pharmaceutical care mode

the rational rate of anticoagulation therapy in patients with acute pulmonary embolism increased from 61.73%（50/81） before implementation to 90.48%（19/21）

the difference was statistically significant（P<0.05）. CONCLUSIONS: According to the Inpatient Pharmaceutical Care Mode for Anticoagulation Therapy in Patients with Acute Pulmonary Embolism

standardized management of patients with acute pulmonary embolism can be performed

which can significantly improve the rationality of application of anticoagulant drugs.