Clinical Study of Gualou Kuanchang Capsules in Promoting Postoperative Gastrointestinal Function Recovery in Patients with Gynecological Abdominal Surgery
PENG Liyan, YIN Shuwang, YU Guilan, et al. Clinical Study of Gualou Kuanchang Capsules in Promoting Postoperative Gastrointestinal Function Recovery in Patients with Gynecological Abdominal Surgery[J]. 2022,22(3):342-344.
PENG Liyan, YIN Shuwang, YU Guilan, et al. Clinical Study of Gualou Kuanchang Capsules in Promoting Postoperative Gastrointestinal Function Recovery in Patients with Gynecological Abdominal Surgery[J]. 2022,22(3):342-344. DOI: 10.14009/j.issn.1672-2124.2022.03.020.
OBJECTIVE: To explore the clinical efficacy of Gualou Kuanchang capsules in promoting postoperative gastrointestinal function recovery in patients with gynecological abdominal surgery. METHODS: Totally 108 patients with gynecological abdominal surgery admitted into this hospital from Mar. 2019 to Dec. 2020 were extracted to be divided into the control group(54 cases) and the study group(54 cases) via the envelope lottery. The control group was given routine treatment
while the study group received Gualou Kuanchang capsules on the basis of the control group. The treatment effect was observed after 7 d. The efficacy
gastrointestinal hormone level
inflammatory factors
clinical indicators(first exhaust time
bowel sound recovery time and defecation time) and adverse drug reactions of two groups were compared. RESULTS: Compared with the control group(77.78%
42/54)
the total clinical effective rate of the study group(96.30%
52/54) was significantly higher
and the difference was statistically significant(P<0.05). After treatment of 7 d
the levels of gastrin
somatostatin and motilin in the study group were significantly higher than those in the control group
while the levels of interleukin 6
tumor necrosis factor α and C-reactive protein were significantly lower than those in the control group
the differences were statistically significant(P<0.05). The incidence of adverse drug reactions in the study group was 3.70%(2/54)
significantly lower than 16.67%(9/54) in the control group
with statistically significant differences(P<0.05). The first exhaust time
bowel sound recovery time and defecation time of the study group were significantly shorter than those of the control group
with statistically significant differences(P<0.05). CONCLUSIONS: Gualou Kuanchang capsules can effectively reduce the inflammatory factors and improve the gastrointestinal function of patients after gynecologic abdominal surgery.
关键词
瓜蒌宽肠胶囊妇科腹部手术胃肠功能疗效
Keywords
Gualou Kuanchang capsulesGynaecologyAbdominal surgeryGastrointestinal function recoveryEfficacy