OBJECTIVE: To rapidly evaluate the efficacy

safety and economical efficiency of Xiyanping injection in the treatment of respiratory system diseases in children

so as to provide evidence-based evidence for clinical rational drug use. METHODS: Wanfang Data

CNKI

CBM

Embase

the Cochrane Library and PubMed were retrieved to collect the health technology assessment（HTA） reports

systematic reviews/Meta-analysis and pharmacoeconomic studies related to Xiyangping injection in the treatment of respiratory system diseases in children. The included data were analyzed and summarized

and quality evaluation was performed on the literature and its methodology. RESULTS: A total of 20 articles were enrolled

15 were systematic reviews/Meta-analysis

5 were pharmacoeconomic studies

and no HTA reports were retrieved. Xiyanping injection alone or in combination with western medicine in the treatment of respiratory system diseases in children can improve the total effective rate

shorten the duration of fever

shorten the relief or disappearance time of cough

lung rales

shortness of breath

dyspnea

sore throat

nasal congestion and runny nose

accelerate the absorption of inflammation（chest X-ray examination）

reduce the serum inflammatory factor levels

shorten the length of stay

and improve the cure rate. Meanwhile

the incidence of adverse drug reactions of Xiyanping injection was significantly lower than or similar to the control group. CONCLUSIONS: Xiyanping jing injection has favorable efficacy in the treatment of respiratory system diseases in children. In the future

more in-depth pharmacoeconomic research and standardized clinical observations and safety evaluations can be carried out for Xiyanping injection

so as to provide the evidence-based evidence of related drug use.