OBJECTIVE: To explore the efficacy of mometasone furoate nasal spray combined with Qingre Bawei capsules in the treatment of allergic rhinitis. METHODS: A total of 120 patients with allergic rhinitis admitted into Qionghai People’s Hospital from Dec. 2017 to Dec. 2020 were extracted to be divided into the observation group and the routine group via the simple randomization method

with 60 cases in each group. The routine group was treated with mometasone furoate nasal spray

while the observation group received Qingre Bawei capsules on the basis of the routine group. The efficacy

adverse drug reactions

improvement of symptoms

immune function [type Ⅱ innate lymphocyte（ ILC2）

dendritic cell（ DC） ]

and physiological state of nasal mucosa[eosinophil count（ EOS count）

mast cell count（ MC count） ] before treatment and after treatment of 1 course and 2 courses in two groups were observed. RESULTS: The total effective rate in the observation group was 96. 67%（ 58/60）

significantly higher than81. 67%（ 49/60） in the routine group

the difference was statistically significant（ P < 0. 05）. The remission time of sneezing

running nose

nasal itching and nasal obstruction in the observation group was significantly shorter than that in the conventional group

the difference was statistically significant（ P < 0. 05）. After treatment of 1 course and 2 courses

the levels of ILC2 and DC in the peripheral blood of two group decreased

and the differences were statistically significant across time

groups and interactions（ P < 0. 05）. After treatment of 1 course and 2 courses

the MC count and EOS count of the nasal mucosa of two groups decreased

and the differences were statistically significant across time

groups and interactions（ P < 0. 05）. The incidences of adverse drug reactions in the observation group and the routine group were respectively 0%（ 0/60） and 1. 67%（ 1/60）

the difference was not statistically significant（ P> 0. 05）. CONCLUSIONS: Mometasone furoate nasal spray combined with Qingre Bawei capsules in the treatment of allergic rhinitis is significant with higher safety

which can further improve the immune function and physiological status of nasal mucosa of patients and promote the rehabilitation.