OBJECTIVE: To probe into the efficacy of Bushen Antai decoction for early threatened abortion patients with kidney deficiency and its effects on serum hormone level and pregnancy outcome. METHODS: A total of 114 patients with early threatened abortion admitted into Anhui Hospital of Integrated Traditional Chinese and Western Medicine from 2019 to 2020 were extracted to be divided into two groups according to the double-blind equal allocation model

57 patients were selected as the study group and 57 patients were selected as the control group. The control group was treated with conventional western medicine

while the study group received Bushen Antai decoction on the basis of the control group

both groups were treated continuously for 21 d. The levels of human chorionic gonadotropin（ HCG）

progesterone（P）

estrogen（ E

2

） and D-dimer（ D-D） were detected before and after treatment in two groups. The clinical symptoms of traditional Chinese medicine of patients with early threatened abortion of kidney deficiency type were graded and quantitatively scored. The clinical efficacy of two groups were compared

the pregnancy outcome was recorded and the success rate of pregnancy was calculated. RESULTS: After treatment

the levels of E

2

P

and HCG in the study group were significantly higher than those in the control group

and the levels of D-D were significantly lower than those in the control group

the differences were statistically significant（ P

<

0. 05）. After treatment

a small amount of vaginal bleeding

lower abdomen pain or swelling

lumbosacral soreness

dizziness

tinnitus

frequent nocturia and fatigue scores in the study group were lower than those in the control group

the differences were statistically significant（ P

<

0. 05）. The total effective rate and pregnancy success rate of the study group were respectively 92. 98%（ 53/57） and 96. 49%（ 55/57）

significantly higher than those of the control group 80. 70%（ 46/57） and 82. 46%（ 47/57）

the differences were statistically significant（ P

<

0. 05）. CONCLUSIONS:Bushen Antai decoction can improve the serum hormone level in early threatened abortion patients with kidney deficiency

improve the blood coagulation and anticoagulation related factors and markers before thrombosis

improve the clinical symptoms of traditional Chinese medicine

facilitate the embryo development

promote the clinical efficacy and pregnancy success rate.