YANG Kuo, GAO Rong, SHEN Baode, et al. Progress of Pharmacological Effects and Mechanism of Hepatic and Renal Damage of Isopsoralen[J]. 2021,21(11):1399-1403.
YANG Kuo, GAO Rong, SHEN Baode, et al. Progress of Pharmacological Effects and Mechanism of Hepatic and Renal Damage of Isopsoralen[J]. 2021,21(11):1399-1403. DOI: 10.14009/j.issn.1672-2124.2021.11.027.
Psoralea corylifolia is a kind of commonly used traditional Chinese medicine in clinic
which has the effects of tonifying kidney and strengthening Yang
securing essence and reducing urination. Along with the increasing reports of hepatic adverse drug reactions induced by the use of traditional Chinese medicine isopsoralen and its compound preparations
the issue of hepatotoxic substance basis of isopsoralen has also been widely concerned by scholars. Isopsoralen is the main active and toxic component of psoralea corylifolia. This thesis mainly reviews the research on isopsoralen by domestic and foreign scholars from 2010 to now
so as to provide theoretical basis for new drug research and safe use of isopsoralen.