CAI Yi, SHEN Jie. Process of Vitamin B12 Deficiency in Patients with Type 2 Diabetes Mellitus Induced by Metformin[J]. 2021,21(8):1021-1024. DOI: 10.14009/j.issn.1672-2124.2021.08.030.
二甲双胍致2型糖尿病患者维生素B12缺乏症的研究进展
摘要
二甲双胍为治疗2型糖尿病的首选药物
其致维生素B12缺乏症的药品不良反应日益受到人们的关注。本文通过检索和回顾分析已发表的文献
对二甲双胍致维生素B12缺乏症的流行病学、作用机制、影响因素以及采取的干预措施进行综述
为二甲双胍的临床合理应用提供参考。
Abstract
Metformin is the drug of choice for the treatment of type 2 diabetes
and the adverse drug reactions of vitamin B
12
deficiency induced by metformin have attracted increasing attention. This paper reviews the epidemiology
mechanism of action
influencing factors and interventions taken for the rational clinical application of metformin by searching and reviewing and analyzing the published literature.