OBJECTIVE: To investigate the application of Chinese patent medicines based on prescription review in outpatient and emergency department of Beijing Friendship Hospital

Capital Medical University（ hereinafter referred to as "our hospital"）

so as to improve the rational drug use

promote the efficacy and safety of drug application

and improve the quality of medical treatment. METHODS: A total of 148 657 prescriptions of Chinese patent medicine in outpatient and emergency departments of our hospital in 2020 were randomly selected and reviewed

classified

summarized and statistically analyzed. RESULTS: Among 148 657 prescriptions of Chinese patent medicine

the patients’ ages were distributed from 2 to 100 years old; there were 60 083 prescriptions（ 40. 42%） for male patients and 88 574 prescriptions（ 59. 58%） for female patients; 148 494 prescriptions were rational

with the rational rate of99. 89%. There were 163 irrational prescriptions

including irrational usage and dosage

improper drug combination

repeated drug application

dosage form or route of administration. CONCLUSIONS: Problems with the prescription of Chinese patent medicine in the outpatient and emergency department of the hospital are mainly due to the prescription of Chinese patent medicine by western physicians. The hospital should further strengthen the prescription intervention measures

enhance the training on the application of Chinese patent medicine for outpatient and emergency clinicians

pay attention to and standardize the rational clinical application of Chinese patent medicine

especially for the rational application of medicines for children

and further improve the rational clinical application of Chinese patent medicine.