OBJECTIVE: To probe into the clinical application of human albumin injection in inpatients of Beijing Hospital（ hereinafter referred to as "our hospital "）

and to evaluate the application rationality

so as to provide reference for clinical treatment. METHODS: Retrospective analysis was adopted

the information system was used to collect the relevant data of inpatients with human albumin injection in our hospital from 2019 to 2020. Excel 2007 and SPSS 21. 0 were used to screen

statistically analyze the patients’ age

clinical diagnosis

medication course

dosage and serum albumin level before medication. RESULTS: From 2019 to 2020

a total of 5 685 inpatients in our hospital used human albumin injection（ with 2 848 cases in 2019 and 2 837 cases in 2020）

including 33 departments

and patients in the thoracic surgery and general surgery were more likely to use the drugs. The majority of personal daily dosage was from20 g to 70 g. The course of medication was mainly 2 d and 3 d. The serum albumin level of most patients before medication was less than 30 g/L. A total of 1 433 cases（ 25. 21%） complied with the seven indications recommended in the drug instructions

mainly for the prevention and treatment of hypoproteinemia and adult respiratory distress syndrome.There were 1 090 cases（ 19. 17%） in line with UHC guideline indications

and the main reason for medication was hypoproteinemia. CONCLUSIONS: Human albumin injection is widely used in our hospital

and there are still some misunderstandings in clinical application. It is necessary to strengthen the supervision of its rational application.Clinicians should strictly grasp the indications of human albumin injection and use drugs with caution.