LI Xuejing, WANG Xianying, QIE Suhui, et al. Pharmacoeconomic Evaluation of Compound Danshen Dropping Pills and Shexiang Baoxin Pills in the Treatment of Unstable Angina Pectoris[J]. 2021,21(5):584-589.
LI Xuejing, WANG Xianying, QIE Suhui, et al. Pharmacoeconomic Evaluation of Compound Danshen Dropping Pills and Shexiang Baoxin Pills in the Treatment of Unstable Angina Pectoris[J]. 2021,21(5):584-589. DOI: 10.14009/j.issn.1672-2124.2021.05.017.
OBJECTIVE: To comprehensively evaluate the clinical effect and economy of compound Danshen dropping pills and Shexiang baoxin pills in the treatment of unstable angina pectoris( UAP). METHODS: CNKI
Wanfang database
VIP database and PubMed were retrieved to collect the randomized controlled trial of compound Danshen dropping pills or Shexiang baoxin pills in the treatment of UAP on the basis of conventional treatment.Bayesian network Meta analysis was performed to compare the clinical effect of two regimens.According to the results of Meta analysis
cost-effectiveness analysis or minimum-cost analysis were selected to compare the economics of two regimens.RESULTS: A total of 53 literature were included
including 8 460 patients with UAP.Meta analysis showed that there was no statistically significant difference in the clinical effectiveness of compound Danshen dropping pills and Shexiang baoxin pills in the treatment of UAP( RR = 0. 96
95% CI = 0. 87-1. 07
P > 0. 05). Minimum cost analysis showed that the treatment cost of compound Danshen dropping pills and Shexiang baoxin pills were respectively121. 7 yuan and 191. 5 yuan.The results of sensitivity analysis proved the robustness of the results.CONCLUSIONS: In the treatment of UAP
compound Danshen dripping pills are more economical than Shexiang baoxin pills. Due to the general quality of the study
this conclusion needs to be further verified by large sample