OBJECTIVE: To improve the quality standard of Yishen Jiangu pills. METHODS: To conduct microscopic identification on radix rehmanniae

semen cuscutae

poria

rhizoma dioscoreae and rhizoma alismatis

to preform thin-layer chromatographic identification on cornus officinalis

rhizoma atractylodis and salviae miltiorrhizae

and the high performance liquid chromatography was adopted to carry out quantitative analysis on monosidine and strychnine in the preparation. RESULTS: The characteristics of microscopic identification of radix rehmanniae

semen cuscutae

poria

rhizoma dioscoreae and rhizoma alismatis were obvious

the spots of thin-layer chromatograms of cornus officinalis

rhizoma atractylodis and salviae miltiorrhizae were clear. The morroniside showed good linearity in the range of 0. 368-0. 828 μg

with r2= 0. 999 9（ n = 6）

the average recovery was 97. 55%

and the RSD = 1. 57%;strychnine showed good linearity in the range of 0. 392-0. 882 μg

with r2= 0. 999 9（ n = 6）

the average recovery was97. 29%

and the RSD = 0. 82%. CONCLUSIONS: This method is comprehensive and accurate

which has effectively improved the quality control of this preparation.