OBJECTIVE: To investigate the rationality of clinical application of compound treotide injection and prescription review in People ’s Hospital of Ningxia Hui Autonomous Region（ hereinafter referred to as "our hospital"）

and explore the intervention mode of our hospital

so as to provide reference for clinical application and management.METHODS: Retrospective investigation and research were used to collect the clinical usage

consumption sum

rational rate of prescriptions of compound treotide injection

and interviews of clinicians in the department of discipline inspection and supervision of our hospital in 2019 for statistical analysis.The application rationality of compound treotide injection in our hospital and the effects of multi-department intervention management mode were evaluated.RESULTS: From Jan.to Jun.2019

the consumption sum of compound treotide injection in our hospital showed an increasing trend

and the maximum consumption sum in a single month was 1 389 700 yuan.In 2019

compound treotide injection was mainly used in 13 departments of our hospital

including 3 surgical departments and10 internal medicine departments.And surgery was the main department

with a total consumption amount of 68.64%（ 5 328 800 yuan/7 763 800 yuan）.From Jul.to Dec.2019

a total of 1 020 outpatient and emergency patients and inpatients received compound treotide injection

among which 237 cases were irrational

and the irrational application rate was 23.24%.The irrational application rate of compound treotide injection was 95.28%（ 101/106） in outpatient and emergency patients

and 14.88%（ 136/914） in inpatients.Inappropriate indications and inappropriate dosage were the main irrational problems.After intervention

the usage and consumption sum（ 2 940 doses

399 800 yuan） of compound triterpene injection in Dec.2019 were decreased by 71.23% compared with that in Jun.2019（ 10 219 doses

1 389 700 yuan）

and the rational prescription rate increased from 69.87%（ 211/302） in Jul.2019 to94.78%（ 109/115） in Dec.2019.After control

various indicators were significantly improved.CONCLUSIONS: The clinical application of compound treotide injection in our hospital is irrational.The effective supervision of compound treotide injection can be achieved through the multi-department intervention management mode

and the rational rate of clinical drug application can be significantly improved.