当归补血汤合二妙散加减联合负压封闭引流技术治疗糖尿病足的疗效观察

张杨; 刘元炜; 王艳; 张凤强

doi:10.14009/j.issn.1672-2124.2021.03.009

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当归补血汤合二妙散加减联合负压封闭引流技术治疗糖尿病足的疗效观察

论著 | 更新时间：2022-10-08

- 当归补血汤合二妙散加减联合负压封闭引流技术治疗糖尿病足的疗效观察
- Efficacy of Danggui Buxue Decoction and Ermiao Powder Combined with Vacuum Sealing Drainage in the Treatment of Diabetic Foot
- 中国医院用药评价与分析 2021年21卷第3期页码：292-294
- 作者机构：
  
  秦皇岛军工医院内分泌科
- 作者简介：
- 基金信息：
  
  河北省中医药类科研计划课题（No.2020368）
- DOI：10.14009/j.issn.1672-2124.2021.03.009
  中图分类号： R259
- 纸质出版日期：2021，
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[1]张杨,刘元炜,王艳,张凤强.当归补血汤合二妙散加减联合负压封闭引流技术治疗糖尿病足的疗效观察[J].中国医院用药评价与分析,2021,21(03):292-294+298.

ZHANG Yang, LIU Yuanwei, WANG Yan, et al. Efficacy of Danggui Buxue Decoction and Ermiao Powder Combined with Vacuum Sealing Drainage in the Treatment of Diabetic Foot[J]. 2021,21(3):292-294.
[1]张杨,刘元炜,王艳,张凤强.当归补血汤合二妙散加减联合负压封闭引流技术治疗糖尿病足的疗效观察[J].中国医院用药评价与分析,2021,21(03):292-294+298. DOI： 10.14009/j.issn.1672-2124.2021.03.009.

ZHANG Yang, LIU Yuanwei, WANG Yan, et al. Efficacy of Danggui Buxue Decoction and Ermiao Powder Combined with Vacuum Sealing Drainage in the Treatment of Diabetic Foot[J]. 2021,21(3):292-294. DOI： 10.14009/j.issn.1672-2124.2021.03.009.

摘要

目的:探讨当归补血汤合二妙散加减联合负压封闭引流（vacuum sealing drainage

VSD）技术治疗糖尿病足（diabetic foot

DF）临床疗效。方法:将秦皇岛军工医院内分泌科2019年2月至2020年3月收治的80例DF患者由随机数字表法分为对照组（40例）和观察组（40例）。对照组患者给予基础治疗、清创换药和VSD技术治疗

观察组患者在对照组的基础上采用当归补血汤合二妙散加减治疗。观察并比较两组患者的临床疗效、间歇性跛行距离增加值、肢体抬高试验（Buerger试验）降低值、踝肱指数（ABI）、创面愈合时间和住院时间、疼痛视觉模拟评分（visual analogue scale

VAS）及血液流变学情况。结果:观察组患者的治疗总有效率为97.50%（39/40）

明显高于对照组的77.50%（31/40）

差异有统计学意义（χ

=7.314

P=0.007）。观察组患者的创面愈合时间及住院时间明显短于对照组

间歇性跛行距离增加值、Buerger试验降低值均高于对照组

差异均有统计学意义（P

0.05）。相比治疗前

两组患者治疗后的VAS评分明显降低

ABI明显升高;且观察组患者的VAS评分明显低于对照组

ABI明显高于对照组

上述差异均有统计学意义（P

0.05）。相比治疗前

两组患者治疗后的全血高切黏度、全血低切黏度、纤维蛋白原及血浆黏度水平明显降低

且观察组患者明显低于对照组

上述差异均有统计学意义（P

0.05）。结论:当归补血汤合二妙散加减联合VSD技术治疗DF的临床疗效确切

能有效减轻患者疼痛

改善其临床症状和指标

调控血液黏度

缩短创面恢复时间和住院时间。

Abstract

OBJECTIVE: To probe into the clinical efficacy of Danggui Buxue decoction and Ermiao powder combined with vacuum sealing drainage（ VSD） in the treatment of diabetic foot（ DF）.METHODS: Totally 80 patients with DF admitted into Qinhuangdao Jungong Hospital from Feb.2019 to Mar.2020 were extracted to be divided into the control group（ n = 40） and the observation group（ n = 40） via the random number table.The control group was treated with basic treatment

debridement and VSD technology

while the observation group received Danggui Buxue decoction and Ermiao powder on the basis of the control group.The clinical efficacy

intermittent claudication distance increment

decrease of Buerger test

ankle brachial index（ ABI）

wound healing time and length of stay

visual analogue scale（ VAS） score and hemorheological indicators of two groups were observed and compared.RESULTS:The total effective rate of the observation group was 97.50%（ 39/40）

significantly higher than that of the control group 77.50%（ 31/40）

the difference was statistically significant（ χ2= 7.314

P = 0.007）.The wound healing time and length of stay of the observation group were significantly shorter than those of the control group

while intermittent claudication distance increment and decrease of Buerger test were higher than those of the control group

the differences were statistically significant（ P < 0.05）.Compared with before treatment

the VAS score decreased significantly and ABI increased significantly in two groups after treatment.The VAS score in the observation group was significantly lower than that in the control group

the ABI was significantly higher than that in the control group

the differences were statistically significant（ P < 0.05）.Compared with before treatment

the whole blood viscosity high shear

whole blood viscosity low shear

fibrinogen and plasma viscosity levels in two groups after treatment decreased significantly

and the observation group was significantly lower than the control group

the differences were statistically significant（ P < 0.05）.CONCLUSIONS: The clinical efficacy of Danggui Buxue decoction and Ermiao powder combined with VSD in the treatment of DF is significant

which can effectively alleviate patients’ pain

improve the clinical symptoms and indicators

regulate the blood viscosity

and shorten the wound recovery time and length of stay.

关键词

当归补血汤二妙散负压封闭引流技术糖尿病足临床疗效

Keywords

Danggui Buxue decoctionErmiao powderVacuum sealing drainage technologyDiabetic footClinical efficacy

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